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contributor authorEvan A. Zamir
contributor authorLarry A. Taber
date accessioned2017-05-09T00:12:15Z
date available2017-05-09T00:12:15Z
date copyrightDecember, 2004
date issued2004
identifier issn0148-0731
identifier otherJBENDY-26409#823_1.pdf
identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/129562
description abstractDuring the morphogenetic process of cardiac looping, the initially straight cardiac tube bends and twists into a curved tube. The biophysical mechanisms that drive looping remain unknown, but the process clearly involves mechanical forces. Hence, it is important to determine mechanical properties of the early heart, which is a muscle-wrapped tube consisting primarily of a thin outer layer of myocardium surrounding a thick extracellular matrix compartment known as cardiac jelly. In this work, we used microindentation experiments and finite element modeling, combined with an inverse computational method, to determine constitutive relations for the myocardium and cardiac jelly at the outer curvature of stage 12 chick hearts. Material coefficients for exponential strain-energy density functions were found by fitting force-displacement and surface displacement data near the indenter. Residual stress in the myocardium also was estimated. These results should be useful for computational models of the looping heart.
publisherThe American Society of Mechanical Engineers (ASME)
titleMaterial Properties and Residual Stress in the Stage 12 Chick Heart During Cardiac Looping
typeJournal Paper
journal volume126
journal issue6
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.1824129
journal fristpage823
journal lastpage830
identifier eissn1528-8951
keywordsStress
keywordsMaterials properties
keywordsDisplacement
keywordsForce AND Density
treeJournal of Biomechanical Engineering:;2004:;volume( 126 ):;issue: 006
contenttypeFulltext


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