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contributor authorJ. C. Masters
contributor authorM. S. Bleiweis
contributor authorA. Yoganathan
contributor authorC. L. Lucas
contributor authorM. Mill
contributor authorM. Ketner
date accessioned2017-05-09T00:12:13Z
date available2017-05-09T00:12:13Z
date copyrightDecember, 2004
date issued2004
identifier issn0148-0731
identifier otherJBENDY-26409#709_1.pdf
identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/129549
description abstractBackground—The total cavopulmonary connection (TCPC), a palliative correction for congenital defects of the right heart, is based on the corrective technique developed by Fontan and Baudet. Research into the TCPC has primarily focused on reducing power loss through the connection as a means to improve patient longevity and quality of life. The goal of our study is to investigate the efficacy of including a caval offset on the hemodynamics and, ultimately, power loss of a connection. As well, we will quantify the effect of vessel wall compliance on these factors and, in addition, the distribution of hepatic blood to the lungs. Methods—We employed a computational fluid dynamic model of blood flow in the TCPC that includes both the non-Newtonian shear thinning characteristics of blood and the nonlinear compliance of vessel tissue. Results—Power loss in the rigid-walled simulations decayed exponentially as caval offset increased. The compliant-walled results, however, showed that after an initial substantial decrease in power loss for offsets up to half the caval diameter, power loss increased slightly again. We also found only minimal mixing in both simulations of all offset models. Conclusions—The increase in power loss beyond an offset of half the caval diameter was due to an increase in the kinetic contribution. Reduced caval flow mixing, on the other hand, was due to the formation of a pressure head in the offset region which acts as a barrier to flow.
publisherThe American Society of Mechanical Engineers (ASME)
titleThe Effect of Incorporating Vessel Compliance in a Computational Model of Blood Flow in a Total Cavopulmonary Connection (TCPC) with Caval Centerline Offset
typeJournal Paper
journal volume126
journal issue6
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.1824126
journal fristpage709
journal lastpage713
identifier eissn1528-8951
keywordsBlood
keywordsEngineering simulation
keywordsPressure
keywordsFlow (Dynamics)
keywordsVessels
keywordsBlood flow
keywordsBiological tissues
keywordsHemodynamics
keywordsPhysiology
keywordsShear (Mechanics)
keywordsLung AND Liver
treeJournal of Biomechanical Engineering:;2004:;volume( 126 ):;issue: 006
contenttypeFulltext


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