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contributor authorG. Wayne Brodland
date accessioned2017-05-09T00:06:52Z
date available2017-05-09T00:06:52Z
date copyrightApril, 2002
date issued2002
identifier issn0148-0731
identifier otherJBENDY-26237#188_1.pdf
identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/126405
description abstractA comprehensive theory, herein named the Differential Interfacial Tension Hypothesis (DITH), for the self-rearrangement of embryonic cells and tissues is presented. These rearrangements include sorting, mixing and formation of checkerboard patterns in heterotypic aggregates of embryonic cells, and total or partial engulfment, separation and dissociation of tissues. This broadly-based theory accounts for the action of all currently known cytoskeletal components and cell adhesion mechanisms. The theory is used to derive conditions for the cell and tissue rearrangements named above. Finite element-based computer simulations involving two or more cell types confirm these conditions.
publisherThe American Society of Mechanical Engineers (ASME)
titleThe Differential Interfacial Tension Hypothesis (DITH): A Comprehensive Theory for the Self-Rearrangement of Embryonic Cells and Tissues
typeJournal Paper
journal volume124
journal issue2
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.1449491
journal fristpage188
journal lastpage197
identifier eissn1528-8951
keywordsComputer simulation
keywordsBiological tissues
keywordsEngineering simulation
keywordsForce
keywordsSurface tension
keywordsJunctions
keywordsMechanisms AND Separation (Technology)
treeJournal of Biomechanical Engineering:;2002:;volume( 124 ):;issue: 002
contenttypeFulltext


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