contributor author | G. Wayne Brodland | |
date accessioned | 2017-05-09T00:06:52Z | |
date available | 2017-05-09T00:06:52Z | |
date copyright | April, 2002 | |
date issued | 2002 | |
identifier issn | 0148-0731 | |
identifier other | JBENDY-26237#188_1.pdf | |
identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/126405 | |
description abstract | A comprehensive theory, herein named the Differential Interfacial Tension Hypothesis (DITH), for the self-rearrangement of embryonic cells and tissues is presented. These rearrangements include sorting, mixing and formation of checkerboard patterns in heterotypic aggregates of embryonic cells, and total or partial engulfment, separation and dissociation of tissues. This broadly-based theory accounts for the action of all currently known cytoskeletal components and cell adhesion mechanisms. The theory is used to derive conditions for the cell and tissue rearrangements named above. Finite element-based computer simulations involving two or more cell types confirm these conditions. | |
publisher | The American Society of Mechanical Engineers (ASME) | |
title | The Differential Interfacial Tension Hypothesis (DITH): A Comprehensive Theory for the Self-Rearrangement of Embryonic Cells and Tissues | |
type | Journal Paper | |
journal volume | 124 | |
journal issue | 2 | |
journal title | Journal of Biomechanical Engineering | |
identifier doi | 10.1115/1.1449491 | |
journal fristpage | 188 | |
journal lastpage | 197 | |
identifier eissn | 1528-8951 | |
keywords | Computer simulation | |
keywords | Biological tissues | |
keywords | Engineering simulation | |
keywords | Force | |
keywords | Surface tension | |
keywords | Junctions | |
keywords | Mechanisms AND Separation (Technology) | |
tree | Journal of Biomechanical Engineering:;2002:;volume( 124 ):;issue: 002 | |
contenttype | Fulltext | |