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contributor authorHelen H. Chen
contributor authorG. Wayne Brodland
date accessioned2017-05-09T00:01:52Z
date available2017-05-09T00:01:52Z
date copyrightAugust, 2000
date issued2000
identifier issn0148-0731
identifier otherJBENDY-25902#394_1.pdf
identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/123357
description abstractA new cell-level finite element formulation is presented and used to investigate how epithelia and other planar collections of viscous cells might deform during events such as embryo morphogenesis and wound healing. Forces arising from cytoskeletal components, cytoplasm viscosity, and cell-cell adhesions are included. Individual cells are modeled using multiple finite elements, and cell rearrangements can occur. Simulations of cell-sheet stretching indicate that the initial stages of sheet stretching are characterized by changes in cell shape, while subsequent stages are governed by cell rearrangement. Inferences can be made from the simulations about the forces that act in real cell sheets when suitable experimental data are available. [S0148-0731(00)01404-7]
publisherThe American Society of Mechanical Engineers (ASME)
titleCell-Level Finite Element Studies of Viscous Cells in Planar Aggregates
typeJournal Paper
journal volume122
journal issue4
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.1286563
journal fristpage394
journal lastpage401
identifier eissn1528-8951
keywordsForce
keywordsDeformation
keywordsEngineering simulation
keywordsFinite element analysis
keywordsShapes AND Viscosity
treeJournal of Biomechanical Engineering:;2000:;volume( 122 ):;issue: 004
contenttypeFulltext


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