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    Effect of Leaflet Type and Leaflet-Stent Attachment Height on Transcatheter Aortic Valve Leaflet Thrombosis Potential 

    Source: Journal of Medical Devices:;2022:;volume( 016 ):;issue: 002:;page 21005-1
    Author(s): Ncho, Beatrice E.; Siefert, Andrew W.; Sadri, Vahid; Ortner, Jillian; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Transcatheter aortic valve replacement devices vary in leaflet material and in the height for which leaflets attach to the stented valve frame. Combinations of these features can influence leaflet dynamics, neo-sinus ...
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    Blood Damage Through a Bileaflet Mechanical Heart Valve: A Quantitative Computational Study Using a Multiscale Suspension Flow Solver 

    Source: Journal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 010:;page 101009
    Author(s): Min Yun, B.; Aidun, Cyrus K.; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Bileaflet mechanical heart valves (BMHVs) are among the most popular prostheses to replace defective native valves. However, complex flow phenomena caused by the prosthesis are thought to induce serious thromboembolic ...
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    Blood Damage Quantification in Cardiovascular Flows Through Medical Devices Using a Novel Suspension Flow Method 

    Source: Journal of Medical Devices:;2013:;volume( 007 ):;issue: 004:;page 40909
    Author(s): Min Yun, B.; Aidun, Cyrus K.; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
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    Mechanics of Healthy and Functionally Diseased Mitral Valves: A Critical Review 

    Source: Journal of Biomechanical Engineering:;2013:;volume( 135 ):;issue: 002:;page 21007
    Author(s): Rabbah, Jean; Saikrishnan, Neelakantan; Siefert, Andrew W.; Santhanakrishnan, Arvind; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The mitral valve is a complex apparatus with multiple constituents that work cohesively to ensure unidirectional flow between the left atrium and ventricle. Disruption to any or all of the components—the annulus, leaflets, ...
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    Design of a Pulsatile Flow Facility to Evaluate Thrombogenic Potential of Implantable Cardiac Devices 

    Source: Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 004:;page 45001
    Author(s): Arjunon, Sivakkumar; Ardana, Pablo Hidalgo; Saikrishnan, Neelakantan; Madhani, Shalv; Foster, Brent; Glezer, Ari; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Due to expensive nature of clinical trials, implantable cardiac devices should first be extensively characterized in vitro. Prosthetic heart valves (PHVs), an important class of these devices, have been shown to be associated ...
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    Role of Mitral Annulus Diastolic Geometry on Intraventricular Filling Dynamics 

    Source: Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 012:;page 121007
    Author(s): Okafor, Ikechukwu U.; Santhanakrishnan, Arvind; Raghav, Vrishank S.; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The mitral valve (MV) is a bileaflet valve positioned between the left atrium and ventricle of the heart. The annulus of the MV has been observed to undergo geometric changes during the cardiac cycle, transforming from a ...
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    Effect of Hinge Gap Width of a St. Jude Medical Bileaflet Mechanical Heart Valve on Blood Damage Potential—An In Vitro Micro Particle Image Velocimetry Study 

    Source: Journal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 009:;page 91008
    Author(s): Jun, Brian H.; Saikrishnan, Neelakantan; Arjunon, Sivakkumar; Min Yun, B.; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The hinge regions of the bileaflet mechanical heart valve (BMHV) can cause blood element damage due to nonphysiological shear stress levels and regions of flow stasis. Recently, a micro particle image velocimetry (خ¼PIV) ...
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    In Vitro Comparison of Doppler and Catheter Measured Pressure Gradients in 3D Models of Mitral Valve Calcification 

    Source: Journal of Biomechanical Engineering:;2013:;volume( 135 ):;issue: 009:;page 94502
    Author(s): Herrmann, Tarrah A.; Siefert, Andrew W.; Pressman, Gregg S.; Gollin, Hannah R.; Touchton, Jr. ,Steven A.; Saikrishnan, Neelakantan; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Mitral annular calcification (MAC) involves calcium deposition in the fibrous annulus supporting the mitral valve (MV). When calcification extends onto the leaflets, valve opening can be restricted. The influence of MAC ...
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    Population Averaged Geometric Model of Mitral Valve From Patient Specific Imaging Data1 

    Source: Journal of Medical Devices:;2015:;volume( 009 ):;issue: 003:;page 30952
    Author(s): Drach, Andrew; Khalighi, Amir H.; ter Huurne, Fleur M.; Lee, Chung; Bloodworth, Charles; Pierce, Eric L.; Jensen, Morten O.; Yoganathan, Ajit P.; Sacks, Michael S.
    Publisher: The American Society of Mechanical Engineers (ASME)
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    On the Simulation of Mitral Valve Function in Health, Disease, and Treatment 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 007:;page 70804
    Author(s): Sacks, Michael S.; Drach, Andrew; Lee, Chung-Hao; Khalighi, Amir H.; Rego, Bruno V.; Zhang, Will; Ayoub, Salma; Yoganathan, Ajit P.; Gorman, Robert C.; Gorman, III, Joseph H.,
    Publisher: American Society of Mechanical Engineers (ASME)
    Abstract: The mitral valve (MV) is the left atrioventricular heart valve that regulates blood flow between the left atrium and left ventricle (LV) during the cardiac cycle. Contrary to the aortic valve (AV), the MV is an intimately ...
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