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    Spectral Bandedness in High-Fidelity Computational Fluid Dynamics Predicts Rupture Status in Intracranial Aneurysms 

    Source: Journal of Biomechanical Engineering:;2022:;volume( 144 ):;issue: 006:;page 61004-1
    Author(s): MacDonald, Daniel E.; Najafi, Mehdi; Temor, Lucas; Steinman, David A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Recent studies using high-fidelity computational fluid dynamics (CFD) have revealed high-frequency flow instabilities consistent with clinical reports of bruits and “musical murmurs”, which have been speculated to contribute ...
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    A Rational Approach to Meshing Cerebral Venous Geometries for High-Fidelity Computational Fluid Dynamics 

    Source: Journal of Biomechanical Engineering:;2023:;volume( 145 ):;issue: 007:;page 74501-1
    Author(s): Haley, Anna L.; Sidora, Gurnish; Cancelliere, Nicole M.; Pereira, Vitor M.; Steinman, David A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Computational fluid dynamics (CFD) of cerebral venous flows has become popular owing to the possibility of using local hemodynamics and hemoacoustics to help diagnose and plan treatments for venous diseases of the brain. ...
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    Characterization of Transition to Turbulence for Blood in a Straight Pipe Under Steady Flow Conditions 

    Source: Journal of Biomechanical Engineering:;2016:;volume( 138 ):;issue: 007:;page 71001
    Author(s): Biswas, Dipankar; Casey, David M.; Crowder, Douglas C.; Steinman, David A.; Yun, Yang H.; Loth, Francis
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Blood is a complex fluid that, among other things, has been established to behave as a shear thinning, nonNewtonian fluid when exposed to low shear rates (SR). Many hemodynamic investigations use a Newtonian fluid to ...
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    Inputs for Subject Specific Computational Fluid Dynamics Simulation of Blood Flow in the Mouse Aorta 

    Source: Journal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 010:;page 101008
    Author(s): Van Doormaal, Mark; Zhou, Yu; Zhang, Xiaoli; Steinman, David A.; Mark Henkelman, R.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Mouse models are an important way for exploring relationships between blood hemodynamics and eventual plaque formation. We have developed a mouse model of aortic regurgitation (AR) that produces large changes in plaque ...
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    Impact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis 

    Source: Journal of Biomechanical Engineering:;2022:;volume( 145 ):;issue: 004:;page 41001-1
    Author(s): Pinto Costa, Rayanne; Nwotchouang, Blaise Simplice Talla; Yao, Junyao; Biswas, Dipankar; Casey, David; McKenzie, Ruel; Sebastian, Frederick; Amini, Rouzbeh; Steinman, David A.; Loth, Francis
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Previous experimental flow studies have demonstrated a delay (∼20%) in transition to turbulence for whole blood compared to a Newtonian analog fluid in both a straight pipe and eccentric stenosis model with ridged walls. ...
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    Transition to Turbulence Downstream of a Stenosis for Whole Blood and a Newtonian Analog Under Steady Flow Conditions 

    Source: Journal of Biomechanical Engineering:;2021:;volume( 144 ):;issue: 003:;page 31008-1
    Author(s): Costa, Rayanne Pinto; Simplice Talla Nwotchouang, Blaise; Yao, Junyao; Biswas, Dipankar; Casey, David; McKenzie, Ruel; Steinman, David A.; Loth, Francis
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Blood, a multiphase fluid comprised of plasma, blood cells, and platelets, is known to exhibit a shear-thinning behavior at low shear rates and near-Newtonian behavior at higher shear rates. However, less is known about ...
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    Variability of Computational Fluid Dynamics Solutions for Pressure and Flow in a Giant Aneurysm: The ASME 2012 Summer Bioengineering Conference CFD Challenge 

    Source: Journal of Biomechanical Engineering:;2013:;volume( 135 ):;issue: 002:;page 21016
    Author(s): Steinman, David A.; Hoi, Yiemeng; Fahy, Paul; Morris, Liam; Walsh, Michael T.; Aristokleous, Nicolas; Anayiotos, Andreas S.; Papaharilaou, Yannis; Arzani, Amirhossein; Shadden, Shawn C.; Berg, Philipp; Janiga, Gأ،bor; Bols, Joris; Segers, Patrick; Bressloff, Neil W.; Cibis, Merih; Gijsen, Frank H.; Cito, Salvatore; Pallarأ©s, Jordi; Browne, Leonard D.; Costelloe, Jennifer A.; Lynch, Adrian G.; Degroote, Joris; Vierendeels, Jan; Fu, Wenyu; Qiao, Aike; Hodis, Simona; Kallmes, David F.; Kalsi, Hardeep; Long, Quan; Kheyfets, Vitaly O.; Finol, Ender A.; Kono, Kenichi; Malek, Adel M.; Lauric, Alexandra; Menon, Prahlad G.; Pekkan, Kerem; Esmaily Moghadam, Mahdi; Marsden, Alison L.; Oshima, Marie; Katagiri, Kengo; Peiffer, Vأ©ronique; Mohamied, Yumnah; Sherwin, Spencer J.; Schaller, Jens; Goubergrits, Leonid; Usera, Gabriel; Mendina, Mariana; Valen; Habets, Damiaan F.; Xiang, Jianping; Meng, Hui; Yu, Yue; Karniadakis, George E.; Shaffer, Nicholas; Loth, Francis
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Stimulated by a recent controversy regarding pressure drops predicted in a giant aneurysm with a proximal stenosis, the present study sought to assess variability in the prediction of pressures and flow by a wide variety ...
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    The Computational Fluid Dynamics Rupture Challenge 2013—Phase II: Variability of Hemodynamic Simulations in Two Intracranial Aneurysms 

    Source: Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 012:;page 121008
    Author(s): Berg, Philipp; Roloff, Christoph; Beuing, Oliver; Voss, Samuel; Sugiyama, Shin; Aristokleous, Nicolas; Anayiotos, Andreas S.; Ashton, Neil; Revell, Alistair; Bressloff, Neil W.; Brown, Alistair G.; Jae Chung, Bong; Cebral, Juan R.; Copelli, Gabriele; Fu, Wenyu; Qiao, Aike; Geers, Arjan J.; Hodis, Simona; Dragomir; Nordahl, Emily; Bora Suzen, Yildirim; Owais Khan, Muhammad; Valen; Kono, Kenichi; Menon, Prahlad G.; Albal, Priti G.; Mierka, Otto; Mأ¼nster, Raphael; Morales, Hernأ،n G.; Bonnefous, Odile; Osman, Jan; Goubergrits, Leonid; Pallares, Jordi; Cito, Salvatore; Passalacqua, Alberto; Piskin, Senol; Pekkan, Kerem; Ramalho, Susana; Marques, Nelson; Sanchi, Stأ©phane; Schumacher, Kristopher R.; Sturgeon, Jess;  vihlovأ،, Helena; Hron, Jaroslav; Usera, Gabriel; Mendina, Mariana; Xiang, Jianping; Meng, Hui; Steinman, David A.; Janiga, Gأ،bor
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: With the increased availability of computational resources, the past decade has seen a rise in the use of computational fluid dynamics (CFD) for medical applications. There has been an increase in the application of CFD ...
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