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RISMyosin Crossbridge, Contractile Unit, and the Mechanism of Contraction in Airway Smooth Muscle: A Mechanical Engineer's Perspective
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Muscle contraction is caused by the action of myosin motors within the structural confines of contractile unit arrays. When the force generated by cyclic interactions between myosin crossbridges and actin filaments is ...
Special Issue: Under the Hood—A Look at the Mechanisms Regulating Lung Function
Publisher: The American Society of Mechanical Engineers (ASME)
Mechanobiology in Medical Diagnostics and Therapy
Publisher: The American Society of Mechanical Engineers (ASME)
Mechanopharmacology and Synergistic Relaxation of Airway Smooth Muscle
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Asthmatic airways are stiffer than normal. We have shown that the cytoskeletal passive stiffness of airway smooth muscle (ASM) can be regulated by intracellular signaling pathways, especially those associated with Rho ...