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    Computational Modeling and Analysis of Murmurs Generated by Modeled Aortic Stenoses 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 004:;page 41007
    Author(s): Zhu, Chi; Seo, Jung-Hee; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In this study, coupled hemodynamic–acoustic simulations are employed to study the generation and propagation of murmurs associated with aortic stenoses where the aorta with a stenosed aortic valve is modeled as a curved ...
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    Computational Modeling and Analysis of Murmurs Generated by Modeled Aortic Stenoses 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 004:;page 41007
    Author(s): Zhu, Chi; Seo, Jung-Hee; Mittal, Rajat
    Publisher: American Society of Mechanical Engineers (ASME)
    Abstract: In this study, coupled hemodynamic–acoustic simulations are employed to study the generation and propagation of murmurs associated with aortic stenoses where the aorta with a stenosed aortic valve is modeled as a curved ...
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    Computational Modeling of Aortic Stenosis With a Reduced Degree-of-Freedom Fluid-Structure Interaction Valve Model 

    Source: Journal of Biomechanical Engineering:;2021:;volume( 144 ):;issue: 003:;page 31012-1
    Author(s): Zhu, Chi; Seo, Jung-Hee; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In this study, a novel reduced degree-of-freedom (rDOF) aortic valve model is employed to investigate the fluid-structure interaction (FSI) and hemodynamics associated with aortic stenosis. The dynamics of the valve leaflets ...
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    Quantifying the Effect of Body Habitus on Cardiac Auscultation Via Computational Hemoacoustics 

    Source: Journal of Biomechanical Engineering:;2022:;volume( 145 ):;issue: 002:;page 24503-1
    Author(s): Lee, David Hojun; Seo, Jung-Hee; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The effect of body habitus on auscultation of heart murmurs is investigated via computational hemoacoustic modeling. The source of the heart murmur is first obtained from a hemodynamic simulation of blood flow through a ...
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    Modeling the Effect of Sleeve Gastrectomy on Gastric Digestion in Stomach: Insights From Multiphase Flow Modeling 

    Source: Journal of Biomechanical Engineering:;2025:;volume( 147 ):;issue: 006:;page 61007-1
    Author(s): Li, Weixuan; Kuhar, Sharun; Seo, Jung-Hee; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The geometry and motility of the stomach play a critical role in the digestion of ingested liquid meals. Sleeve gastrectomy, a common type of bariatric surgery used to reduce the size of the stomach, significantly alters ...
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    A Computational Method for Analyzing the Biomechanics of Arterial Bruits 

    Source: Journal of Biomechanical Engineering:;2017:;volume( 139 ):;issue: 005:;page 51008
    Author(s): Zhu, Chi; Seo, Jung-Hee; Bakhshaee, Hani; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: A computational framework consisting of a one-way coupled hemodynamic–acoustic method and a wave-decomposition based postprocessing approach is developed to investigate the biomechanics of arterial bruits. This framework ...
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    Freeman Scholar Lecture (2021)—Sharp-Interface Immersed Boundary Methods in Fluid Dynamics 

    Source: Journal of Fluids Engineering:;2025:;volume( 147 ):;issue: 003:;page 30801-1
    Author(s): Mittal, Rajat; Seo, Jung-Hee; Turner, Jacob; Kumar, Sushrut; Prakhar, Suryansh; Zhou, Ji
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Immersed boundary methods (IBMs) have evolved over the past 50 years from a specialized technique in biofluid dynamics and applied mathematics to a cornerstone of computational fluid dynamics. Many recent advancements in ...
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    Computational Study on the Effects of Valve Orientation on the Hemodynamics and Leaflet Dynamics of Bioprosthetic Pulmonary Valves 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 012:;page 121002-1
    Author(s): Ko, Kwang Bem; Seo, Jung-Hee; Doshi, Ashish; Sen, Danielle Gottlieb; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Pulmonary valves do not display a fibrous annulus as do other valves in the heart; thus, pulmonary valves can be implanted at multiple orientations and locations within the right ventricular outflow tract (RVOT). This gives ...
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    Flow Dynamics in the Aortic Arch and Its Effect on the Arterial Input Function in Cardiac Computed Tomography 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 010:;page 104501
    Author(s): Eslami, Parastou; Seo, Jung-Hee; Lardo, Albert C.; Chen, Marcus Y.; Mittal, Rajat
    Publisher: American Society of Mechanical Engineers (ASME)
    Abstract: The arterial input function (AIF)—time-density curve (TDC) of contrast at the coronary ostia—plays a central role in contrast enhanced computed tomography angiography (CTA). This study employs computational modeling in a ...
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    A Noninvasive Assessment of Flow Based on Contrast Dispersion in Computed Tomography Angiography: A Computational and Experimental Phantom Study 

    Source: Journal of Biomechanical Engineering:;2022:;volume( 144 ):;issue: 009:;page 91009-1
    Author(s): Eslami, Parastou; Seo, Jung-Hee; Rahsepar, Amir Ali; Shafique, Asim; Rollison, Shirley F.; Lardo, Albert C.; Mittal, Rajat; Chen, Marcus Y.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Transluminal attenuation gradient (TAG), defined as the gradient of the contrast agent attenuation drop along the vessel, is an imaging biomarker that indicates stenosis in the coronary arteries. The transluminal attenuation ...
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