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Influence of Tensile Strain on Smooth Muscle Cell Orientation in Rat Blood Vessels
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Blood vessels are subject to tensile stress and associated strain which may influence the structure and organization of smooth muscle cells (SMCs) during physiological development and pathological ...
Relationship Between Hypertension, Hypertrophy, and Opening Angle of Zero-Stress State of Arteries Following Aortic Constriction
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Examination of changes occurring in the zero-stress state of an organ provides a way to study cellular growth in the organ due to change of physical stresses. The zero-stress state of the ...
Elementary Mechanics of the Endothelium of Blood Vessels
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The endothelium lining human arteries is a continuum of endothelial cells. The flowing blood imposes a shear stress on the endothelium. To compute the internal stress in the endothelium, we ...
Zero-Stress States of Arteries
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The no-load configuration of a living organ is, in general, not the zero-stress state. The difference can be revealed by cutting up an unloaded organ to such an extent that the stress becomes ...
Control of the Shape of a Thrombus-Neointima-Like Structure by Blood Shear Stress
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Fluid mechanical factors are thought to influence vascular morphogenesis. Here we show how blood shear stress regulates the shape of a thrombus-neointima-like tissue on a polymer micro-cylinder ...
Prevention of Mechanical Stretch-Induced Endothelial and Smooth Muscle Cell Injury in Experimental Vein Grafts
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Vein grafts are subject to increased tensile stress due to exposure to arterial blood pressure, which has been hypothesized to induce endothelial cell (EC) and smooth muscle cell (SMC) injury. ...
The Zero-Stress State of Rat Veins and Vena Cava
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The zero-stress state of a vein is, like that of an artery, not a closed cylindrical tube, but is a series of segments whose cross-sections are open sectors. An opening angle of each sector ...
A Hypothesis on the Mechanism of Trauma of Lung Tissue Subjected to Impact Load
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: When a compressive impact load is applied on the chest, as in automobile crash or bomb explosion, the lung may be injured and show evidences of edema and hemorrhage. Since soft tissues have ...