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Influence of Stress Magnitude on Water Loss and Chondrocyte Viability in Impacted Articular Cartilage
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The objective of this study was to assess mechano-biological response of articular cartilage when subjected to a single impact stress. Mature bovine cartilage explants were impacted with peak ...
Deformation-Dependent Enzyme Mechanokinetic Cleavage of Type I Collagen
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Collagen is a key structural protein in the extracellular matrix of many tissues. It provides biological tissues with tensile mechanical strength and is enzymatically cleaved by a class of ...
A Novel Device to Apply Controlled Flexion and Extension to the Rat Knee Following Anterior Cruciate Ligament Reconstruction
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: We designed and validated a novel device for applying flexion-extension cycles to a rat knee in an in vivo model of anterior cruciate ligament reconstruction (ACL-R). Our device is intended ...
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