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Microdamage and Osteocyte-Lacuna Strain in Bone: A Microstructural Finite Element Analysis
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Damage accumulation in living tissues occurs when the rate of damage formation is greater than the rate of damage repair. For very large increases in the loading rate of bones, this can ...
Evaluation of Cement Stresses in Finite Element Analyses of Cemented Orthopaedic Implants
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Stress analysis of the cement fixation of orthopaedic implants to bone is frequently carried out using finite element analysis. However, the stress distribution in the cement layer is usually ...
An Analysis of Crack Propagation Paths at Implant/ Bone-Cement Interfaces
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Clinical follow-up studies of joint replacements indicate that debonding of the implant from the bone-cement is the first mechanical event of loosening. Debonding can occur due to unsustainable ...
Three-Dimensional Finite Element Analysis of Glenoid Replacement Prostheses: A Comparison of Keeled and Pegged Anchorage Systems
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Glenoid component loosening is the dominant cause of failure in total shoulder arthroplasty. It is presumed that loosening in the glenoid is caused by high stresses in the cement layer. Several ...
Mechanisms of Strain-Mediated Mesenchymal Stem Cell Apoptosis
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Mechanical conditioning of mesenchymal stem cells (MSCs) has been adopted widely as a biophysical signal to aid tissue engineering applications. The replication of in vivo mechanical signaling ...
Computational Mechanobiology to Study the Effect of Surface Geometry on Peri-Implant Tissue Differentiation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The geometry of an implant surface to best promote osseointegration has been the subject of several experimental studies, with porous beads and woven mesh surfaces being among the options ...
Design and Validation of a Machine for Reproducible Precision Insertion of Femoral Hip Prostheses for Preclinical Testing
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Preclinical testing of orthopaedic implants is becoming increasingly important to eliminate inferior designs before animal experiments or clinical trials are begun. Preclinical tests can include ...
Analysis of Prolapse in Cardiovascular Stents: A Constitutive Equation for Vascular Tissue and Finite-Element Modelling
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The effectiveness of a cardiovascular stent depends on many factors, such as its ability to sustain the compression applied by the vessel wall, minimal longitudinal contraction when it is ...
A Finite Element Prediction of Strain on Cells in a Highly Porous Collagen-Glycosaminoglycan Scaffold
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Tissue engineering often involves seeding cells into porous scaffolds and subjecting the scaffold to mechanical stimulation. Current experimental techniques have provided a plethora of data regarding ...