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    Computational Study of Hemodynamic Effects of Abnormal E/A Ratio on Left Ventricular Filling 

    Source: Journal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 006:;page 61005
    Author(s): Zheng, Xudong; Xue, Qian; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Threedimensional numerical simulations are employed to investigate the hemodynamic effects of abnormal E/A ratios on left ventricular filling. The simulations are performed in a simplified geometric model of the left ...
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    Computational Modeling and Analysis of Murmurs Generated by Modeled Aortic Stenoses 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 004:;page 41007
    Author(s): Zhu, Chi; Seo, Jung-Hee; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In this study, coupled hemodynamic–acoustic simulations are employed to study the generation and propagation of murmurs associated with aortic stenoses where the aorta with a stenosed aortic valve is modeled as a curved ...
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    Computational Modeling and Analysis of Murmurs Generated by Modeled Aortic Stenoses 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 004:;page 41007
    Author(s): Zhu, Chi; Seo, Jung-Hee; Mittal, Rajat
    Publisher: American Society of Mechanical Engineers (ASME)
    Abstract: In this study, coupled hemodynamic–acoustic simulations are employed to study the generation and propagation of murmurs associated with aortic stenoses where the aorta with a stenosed aortic valve is modeled as a curved ...
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    Computational Modeling of Aortic Stenosis With a Reduced Degree-of-Freedom Fluid-Structure Interaction Valve Model 

    Source: Journal of Biomechanical Engineering:;2021:;volume( 144 ):;issue: 003:;page 31012-1
    Author(s): Zhu, Chi; Seo, Jung-Hee; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In this study, a novel reduced degree-of-freedom (rDOF) aortic valve model is employed to investigate the fluid-structure interaction (FSI) and hemodynamics associated with aortic stenosis. The dynamics of the valve leaflets ...
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    Quantifying the Effect of Body Habitus on Cardiac Auscultation Via Computational Hemoacoustics 

    Source: Journal of Biomechanical Engineering:;2022:;volume( 145 ):;issue: 002:;page 24503-1
    Author(s): Lee, David Hojun; Seo, Jung-Hee; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The effect of body habitus on auscultation of heart murmurs is investigated via computational hemoacoustic modeling. The source of the heart murmur is first obtained from a hemodynamic simulation of blood flow through a ...
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    Hemodynamics in the Left Atrium and Its Effect on Ventricular Flow Patterns 

    Source: Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 011:;page 111003
    Author(s): Vedula, Vijay; George, Richard; Younes, Laurent; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In the present study, we investigate the hemodynamics inside left atrium (LA) and understand its impact on the development of ventricular flow patterns. We construct the heart model using dynamiccomputed tomographic images ...
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    A Computational Method for Analyzing the Biomechanics of Arterial Bruits 

    Source: Journal of Biomechanical Engineering:;2017:;volume( 139 ):;issue: 005:;page 51008
    Author(s): Zhu, Chi; Seo, Jung-Hee; Bakhshaee, Hani; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: A computational framework consisting of a one-way coupled hemodynamic–acoustic method and a wave-decomposition based postprocessing approach is developed to investigate the biomechanics of arterial bruits. This framework ...
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    Computational Study on the Effects of Valve Orientation on the Hemodynamics and Leaflet Dynamics of Bioprosthetic Pulmonary Valves 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 012:;page 121002-1
    Author(s): Ko, Kwang Bem; Seo, Jung-Hee; Doshi, Ashish; Sen, Danielle Gottlieb; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Pulmonary valves do not display a fibrous annulus as do other valves in the heart; thus, pulmonary valves can be implanted at multiple orientations and locations within the right ventricular outflow tract (RVOT). This gives ...
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    Freeman Scholar Lecture (2021)—Sharp-Interface Immersed Boundary Methods in Fluid Dynamics 

    Source: Journal of Fluids Engineering:;2025:;volume( 147 ):;issue: 003:;page 30801-1
    Author(s): Mittal, Rajat; Seo, Jung-Hee; Turner, Jacob; Kumar, Sushrut; Prakhar, Suryansh; Zhou, Ji
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Immersed boundary methods (IBMs) have evolved over the past 50 years from a specialized technique in biofluid dynamics and applied mathematics to a cornerstone of computational fluid dynamics. Many recent advancements in ...
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    Computational Study of Computed Tomography Contrast Gradients in Models of Stenosed Coronary Arteries 

    Source: Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 009:;page 91002
    Author(s): Eslami, Parastou; Seo, Jung; Rahsepar, Amir Ali; George, Richard; Lardo, Albert C.; Mittal, Rajat
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Recent computed tomography coronary angiography (CCTA) studies have noted higher transluminal contrast agent gradients in arteries with stenotic lesions, but the physical mechanism responsible for these gradients is not ...
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