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    Finite Element Implementation of Biphasic-Fluid Structure Interactions in febio 

    Source: Journal of Biomechanical Engineering:;2021:;volume( 143 ):;issue: 009:;page 091005-1
    Author(s): Shim, Jay J.; Maas, Steve A.; Weiss, Jeffrey A.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In biomechanics, solid–fluid mixtures have commonly been used to model the response of hydrated biological tissues. In cartilage mechanics, this type of mixture, where the fluid and solid constituents are both assumed to ...
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    Modeling Fatigue Failure of Cartilage and Fibrous Biological Tissues Using Constrained Reactive Mixture Theory 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 012:;page 121001-1
    Author(s): Zimmerman, Brandon K.; Maas, Steve A.; Weiss, Jeffrey A.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Fatigue failure in biological soft tissues plays a critical role in the etiology of chronic soft tissue injuries and diseases such as osteoarthritis (OA). Understanding failure mechanisms is hindered by the decades-long ...
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    Finite Element Implementation of Computational Fluid Dynamics With Reactive Neutral and Charged Solute Transport in FEBio 

    Source: Journal of Biomechanical Engineering:;2023:;volume( 145 ):;issue: 009:;page 91011-1
    Author(s): Shim, Jay J.; Maas, Steve A.; Weiss, Jeffrey A.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The objective of this study was to implement a novel fluid-solutes solver into the open-source finite element software FEBio, that extended available modeling capabilities for biological fluids and fluid-solute mixtures. ...
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    Erratum: “A Numerical Scheme for Anisotropic Reactive Nonlinear Viscoelasticity” [ASME J. Biomech Eng., 2023, 145(1), p. 011004; DOI: 10.1115/1.4054983] 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 010:;page 107001-1
    Author(s): Ateshian, Gerard A.; Petersen, Courtney A.; Maas, Steve A.; Weiss, Jeffrey A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In this erratum, we correct a mistake in a subcomponent of the numerical algorithm proposed in our recent study for modeling anisotropic reactive nonlinear viscoelasticity (doi:10.1115/1.4054983), for the special case where ...
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    Finite Element Formulation of Multiphasic Shell Elements for Cell Mechanics Analyses in FEBio 

    Source: Journal of Biomechanical Engineering:;2018:;volume( 140 ):;issue: 012:;page 121009
    Author(s): Hou, Jay C.; Maas, Steve A.; Weiss, Jeffrey A.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: With the recent implementation of multiphasic materials in the open-source finite element (FE) software FEBio, three-dimensional (3D) models of cells embedded within the tissue may now be analyzed, accounting for porous ...
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    Finite Element Framework for Computational Fluid Dynamics in FEBio 

    Source: Journal of Biomechanical Engineering:;2018:;volume( 140 ):;issue: 002:;page 21001
    Author(s): Ateshian, Gerard A.; Shim, Jay J.; Maas, Steve A.; Weiss, Jeffrey A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The mechanics of biological fluids is an important topic in biomechanics, often requiring the use of computational tools to analyze problems with realistic geometries and material properties. This study describes the ...
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    A Formulation for Fluid–Structure Interactions in febio Using Mixture Theory 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 005:;page 51010
    Author(s): Shim, Jay J.; Maas, Steve A.; Weiss, Jeffrey A.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Many physiological systems involve strong interactions between fluids and solids, posing a significant challenge when modeling biomechanics. The objective of this study was to implement a fluid–structure interaction (FSI) ...
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    A Formulation for Fluid–Structure Interactions in febio Using Mixture Theory 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 005:;page 51010
    Author(s): Shim, Jay J.; Maas, Steve A.; Weiss, Jeffrey A.; Ateshian, Gerard A.
    Publisher: American Society of Mechanical Engineers (ASME)
    Abstract: Many physiological systems involve strong interactions between fluids and solids, posing a significant challenge when modeling biomechanics. The objective of this study was to implement a fluid–structure interaction (FSI) ...
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    Damage Mechanics of Biological Tissues in Relation to Viscoelasticity 

    Source: Journal of Biomechanical Engineering:;2022:;volume( 145 ):;issue: 004:;page 41011-1
    Author(s): Ateshian, Gerard A.; Kroupa, Kimberly R.; Petersen, Courtney A.; Zimmerman, Brandon K.; Maas, Steve A.; Weiss, Jeffrey A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: This study examines the theoretical foundations for the damage mechanics of biological tissues in relation to viscoelasticity. Its primary goal is to provide a mechanistic understanding of well-known experimental observations ...
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    Mechanical Interaction of Angiogenic Microvessels With the Extracellular Matrix 

    Source: Journal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 002:;page 21001
    Author(s): Edgar, Lowell T.; Hoying, James B.; Utzinger, Urs; Underwood, Clayton J.; Krishnan, Laxminarayanan; Baggett, Brenda K.; Maas, Steve A.; Guilkey, James E.; Weiss, Jeffrey A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Angiogenesis is the process by which new blood vessels sprout from existing blood vessels, enabling new vascular elements to be added to an existing vasculature. This review discusses our investigations into the role of ...
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