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A Framework for In Silico Clinical Trials for Medical Devices Using Concepts From Model Verification, Validation, and Uncertainty Quantification
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The rising costs of clinical trials for medical devices in recent years has led to an increased interest in what are called in silico clinical trials, where simulation results are used to supplement or to replace those ...
Finite Element Model of the Knee for Investigation of Injury Mechanisms: Development and Validation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Multiple computational models have been developed to study knee biomechanics. However, the majority of these models are mainly validated against a limited range of loading conditions and/or do not include sufficient details ...