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    Nanoparticle Redistribution in PC3 Tumors Induced by Local Heating in Magnetic Nanoparticle Hyperthermia: In Vivo Experimental Study 

    Source: Journal of Heat Transfer:;2019:;volume( 141 ):;issue: 003:;page 32402
    Author(s): Gu, Qimei; Joglekar, Tejashree; Bieberich, Charles; Ma, Ronghui; Zhu, Liang
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In magnetic nanoparticle hyperthermia, a required thermal dosage for tumor destruction greatly depends on nanoparticle distribution in tumors. The objective of this study is to conduct in vivo experiments to evaluate whether ...
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    Heating Protocol Design Affected by Nanoparticle Redistribution and Thermal Damage Model in Magnetic Nanoparticle Hyperthermia for Cancer Treatment 

    Source: Journal of Heat Transfer:;2020:;volume( 142 ):;issue: 007:;page 072501-1
    Author(s): Singh, Manpreet; Gu, Qimei; Ma, Ronghui; Zhu, Liang
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Recent micro-CT scans have demonstrated a much larger magnetic nanoparticle distribution volume in tumors after localized heating than those without heating, suggesting possible heating-induced nanoparticle migration. In ...
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    Mild Whole-Body Hyperthermia-Induced Interstitial Fluid Pressure Reduction and Enhanced Nanoparticle Delivery to PC3 Tumors: In Vivo Studies and Micro-Computed Tomography Analyses 

    Source: Journal of Thermal Science and Engineering Applications:;2020:;volume( 012 ):;issue: 006:;page 061001-1
    Author(s): Gu, Qimei; Liu, Shuaishuai; Saha Ray, Arunendra; Florinas, Stelios; Christie, Ronald James; Daniel, Marie-Christine; Bieberich, Charles; Ma, Ronghui; Zhu, Liang
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In this study, we performed in vivo experiments on mice to evaluate whether whole-body hyperthermia enhances nanoparticle delivery to PC3 (prostatic cancer) tumors. PC3 xenograft tumors in immunodeficient mice were used ...
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