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RISThe Influence of Axial Compression on the Cellular and Mechanical Function of Spinal Tissues; Emphasis on the Nucleus Pulposus and Annulus Fibrosus: A Review
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: In light of the correlation between chronic back pain and intervertebral disc (IVD) degeneration, this literature review seeks to illustrate the importance of the hydraulic response across the nucleus pulposus (NP)-annulus ...
How Static and Cyclic Loading Affect the Mechanical Properties of the Porcine Annulus Fibrosus
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: This study sought to evaluate the effects of prolonged cyclic loading on the tissue-level mechanical properties of the spinal annulus fibrosus. Functional spinal units (FSUs) were obtained from porcine cervical spines at ...
Does Annulus Fibrosus Lamellar Adhesion Testing Require Preconditioning?
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The interlamellar matrix (ILM), located between the annular layers of the intervertebral disc (IVD), is an adhesive component which acts to resist delamination. Investigating the mechanical properties of the ILM can provide ...
Mechanical Consequence of Induced Intervertebral Disc Degeneration in the SPARC-Null Mouse
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Intervertebral disc (IVD) degeneration is associated with low back pain (LBP) and accompanied by mechanical changes to the spine. Secreted protein acidic and rich in cysteine (SPARC) is a protein that contributes to the ...
Unloaded Organ Culturing Has a Detrimental Effect on the Axial Mechanical Properties of the Intervertebral Disc
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Healthy function of intervertebral discs (IVDs) depends on their tissue mechanical properties. Native cells embedded within IVD tissues are responsible for building, maintaining, and repairing IVD structures in response ...