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RISAn Axisymmetric Boundary Integral Model for Incompressible Linear Viscoelasticity: Application to the Micropipette Aspiration Contact Problem
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The micropipette aspiration test has been used extensively in recent years as a means of quantifying cellular mechanics and molecular interactions at the microscopic scale. However, previous ...
An Axisymmetric Boundary Integral Model for Assessing Elastic Cell Properties in the Micropipette Aspiration Contact Problem
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The micropipette aspiration technique has been used extensively in recent years to measure the mechanical properties of living cells. In the present study, a boundary integral formulation with ...
Editorial
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: This special issue of the ASME JOURNAL OF BIOMECHANICAL ENGINEERING features articles on various aspects of cellular and tissue engineering. These studies were part of a symposium entitled “Cell ...
An Axisymmetric Boundary Element Model for Determination of Articular Cartilage Pericellular Matrix Properties In Situ via Inverse Analysis of Chondron Deformation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The pericellular matrix (PCM) is the narrow tissue region surrounding all chondrocytes in articular cartilage and, together, the chondrocyte(s) and surrounding PCM have been termed the chondron. ...
The Dynamic Mechanical Environment of the Chondrocyte: A Biphasic Finite Element Model of Cell-Matrix Interactions Under Cyclic Compressive Loading
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Cyclic mechanical loading of articular cartilage results in a complex biomechanical environment at the scale of the chondrocytes that strongly affects cellular metabolic activity. Under dynamic ...
Functional Tissue Engineering: The Role of Biomechanics
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: “Tissue engineering” uses implanted cells, scaffolds, DNA, protein, and/or protein fragments to replace or repair injured or diseased tissues and organs. Despite its early success, tissue engineers ...
Compressive Properties of Mouse Articular Cartilage Determined in a Novel Micro-Indentation Test Method and Biphasic Finite Element Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The mechanical properties of articular cartilage serve as important measures of tissue function or degeneration, and are known to change significantly with osteoarthritis. Interest in small animal ...
Microscale Diffusion Properties of the Cartilage Pericellular Matrix Measured Using 3D Scanning Microphotolysis
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Chondrocytes, the cells in articular cartilage, are enclosed within a pericellular matrix (PCM) whose composition and structure differ from those of the extracellular matrix (ECM). Since the PCM ...
Alterations in the Mechanical Properties of the Human Chondrocyte Pericellular Matrix With Osteoarthritis
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: In articular cartilage, chondrocytes are surrounded by a pericellular matrix (PCM), which together with the chondrocyte have been termed the “chondron.” While the precise function of the PCM is ...
The Micromechanical Environment of Intervertebral Disc Cells Determined by a Finite Deformation, Anisotropic, and Biphasic Finite Element Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Cellular response to mechanical loading varies between the anatomic zones of the intervertebral disc. This difference may be related to differences in the structure and mechanics of both cells ...