Abstract: Computational design is growing in necessity for advancing biomedical technologies, particularly for complex systems with numerous trade-offs. For instance, in tissue scaffolds constructed from repeating unit cells, the ...

Abstract: Computational approaches have great potential for aiding clinical product development by finding promising candidate designs prior to expensive testing and clinical trials. Here, an approach for designing multilevel bone ...

Abstract: Advances in three-dimensional (3D) printing are enabling the design and fabrication of tailored lattices with high mechanical efficiency. Here, we focus on conducting experiments to mechanically characterize lattice ...

Abstract: The process of designing integrated biological systems across scales is difficult, with challenges arising from the modeling, understanding, and search of complex system design spaces. This paper explores these challenges ...