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Reduced Smooth Muscle Contractile Capacity Facilitates Maladaptive Arterial Remodeling
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Albeit seldom considered explicitly, the vasoactive state of a central artery can contribute to luminal control and thereby affect the in vivo values of flow-induced wall shear stress and pressure-induced intramural stress, ...
Pulsatile Perfusion Bioreactor for Biomimetic Vascular Impedances
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Pulsatile waves of blood pressure and flow are continuously augmented by the resistance, compliance, and inertance properties of the vasculature, resulting in unique wave characteristics at distinct anatomical locations. ...
Contractile Smooth Muscle and Active Stress Generation in Porcine Common Carotids
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The mechanical response of intact blood vessels to applied loads can be delineated into passive and active components using an isometric decomposition approach. Whereas the passive response is due predominantly to the ...