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RISFunctional Tissue Engineering: The Role of Biomechanics
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: “Tissue engineering” uses implanted cells, scaffolds, DNA, protein, and/or protein fragments to replace or repair injured or diseased tissues and organs. Despite its early success, tissue engineers ...
Effect of Implanting a Soft Tissue Autograft in a Central-Third Patellar Tendon Defect: Biomechanical and Histological Comparisons
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Previous studies by our laboratory have demonstrated that implanting a stiffer tissue engineered construct at surgery is positively correlated with repair tissue stiffness at 12 weeks. The objective ...
Effect of Surgery to Implant Motion and Force Sensors on Vertical Ground Reaction Forces in the Ovine Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Activities of daily living (ADLs) generate complex, multidirectional forces in the anterior cruciate ligament (ACL). While calibration problems preclude direct measurement in patients, ACL forces ...
Mechanical Stimulation of Tendon Tissue Engineered Constructs: Effects on Construct Stiffness, Repair Biomechanics, and Their Correlation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The objective of this study was to determine how in vitro mechanical stimulation of tissue engineered constructs affects their stiffness and modulus in culture and tendon repair biomechanics ...
Mechanical Stimulation of Tissue Engineered Tendon Constructs: Effect of Scaffold Materials
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Our group has shown that numerous factors can influence how tissue engineered tendon constructs respond to in vitro mechanical stimulation. Although one study showed that stimulating mesenchymal ...