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    Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 006:;page 60901-1
    Author(s): Kailash, Keshav A.; Hawes, Jie Z.; Cocciolone, Austin J.; Bersi, Matthew R.; Mecham, Robert P.; Wagenseil, Jessica E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Arterial stiffening occurs during natural aging, is associated with an increased risk of adverse cardiovascular events, and can follow different timelines in males and females. One mechanism of arterial stiffening includes ...
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    Elastic Fiber Fragmentation Increases Transmural Hydraulic Conductance and Solute Transport in Mouse Arteries 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 002:;page 21013
    Author(s): Cocciolone, Austin J.; Johnson, Elizabeth O.; Shao, Jin-Yu; Wagenseil, Jessica E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Transmural advective transport of solute and fluid was investigated in mouse carotid arteries with either a genetic knockout of fibulin-5 (Fbln5−/−) or treatment with elastase to determine the influence of a disrupted ...
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    Effects of Increased Arterial Stiffness on Atherosclerotic Plaque Amounts 

    Source: Journal of Biomechanical Engineering:;2018:;volume( 140 ):;issue: 005:;page 51007
    Author(s): Stoka, Kellie V.; Maedeker, Justine A.; Bennett, Lisa; Bhayani, Siddharth A.; Gardner, William S.; Procknow, Jesse D.; Cocciolone, Austin J.; Walji, Tezin A.; Craft, Clarissa S.; Wagenseil, Jessica E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Increased arterial stiffness is associated with atherosclerosis in humans, but there have been limited animal studies investigating the relationship between these factors. We bred elastin wildtype (Eln+/+) and heterozygous ...
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