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Thermodynamic Nonequilibrium Phase Change Behavior and Thermal Properties of Biological Solutions for Cryobiology Applications
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Understanding the phase change behavior of biomaterials during freezing/thawing including their thermal properties at low temperatures is essential to design and improve cryobiology applications ...
Freezing-Assisted Intracellular Drug Delivery to Multidrug Resistant Cancer Cells
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The efficacy of chemotherapy is significantly impaired by the multidrug resistance (MDR) of cancer cells. The mechanism of MDR is associated with the overexpression of certain adenosine ...
Biphasic Investigation of Tissue Mechanical Response During Freezing Front Propagation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Cryopreservation of engineered tissue (ET) has achieved limited success due to limited understanding of freezing-induced biophysical phenomena in ETs, especially fluid-matrix interaction within ETs. ...
Spatiotemporal Measurement of Freezing-Induced Deformation of Engineered Tissues
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: In order to cryopreserve functional engineered tissues (ETs), the microstructure of the extracellular matrix (ECM) should be maintained, as well as the cellular viability since the functionality ...
Freezing-Induced Fluid-Matrix Interaction in Poroelastic Material
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Freezing of biological tissue is emerging in various biomedical applications. The success of these applications requires precise control of the tissue functionality, which is closely associated ...