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    Thermodynamic Nonequilibrium Phase Change Behavior and Thermal Properties of Biological Solutions for Cryobiology Applications 

    Source: Journal of Biomechanical Engineering:;2004:;volume( 126 ):;issue: 002:;page 196
    Author(s): Bumsoo Han; John C. Bischof
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Understanding the phase change behavior of biomaterials during freezing/thawing including their thermal properties at low temperatures is essential to design and improve cryobiology applications ...
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    Freezing-Assisted Intracellular Drug Delivery to Multidrug Resistant Cancer Cells 

    Source: Journal of Biomechanical Engineering:;2009:;volume( 131 ):;issue: 007:;page 74513
    Author(s): Ka Yaw Teo; Bumsoo Han
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The efficacy of chemotherapy is significantly impaired by the multidrug resistance (MDR) of cancer cells. The mechanism of MDR is associated with the overexpression of certain adenosine ...
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    Biphasic Investigation of Tissue Mechanical Response During Freezing Front Propagation 

    Source: Journal of Biomechanical Engineering:;2012:;volume( 134 ):;issue: 006:;page 61005
    Author(s): Jamie Wright; Bumsoo Han; Cheng-Jen Chuong
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Cryopreservation of engineered tissue (ET) has achieved limited success due to limited understanding of freezing-induced biophysical phenomena in ETs, especially fluid-matrix interaction within ETs. ...
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    Spatiotemporal Measurement of Freezing-Induced Deformation of Engineered Tissues 

    Source: Journal of Biomechanical Engineering:;2010:;volume( 132 ):;issue: 003:;page 31003
    Author(s): Ka Yaw Teo; J. Craig Dutton; Bumsoo Han
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In order to cryopreserve functional engineered tissues (ETs), the microstructure of the extracellular matrix (ECM) should be maintained, as well as the cellular viability since the functionality ...
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    Freezing-Induced Fluid-Matrix Interaction in Poroelastic Material 

    Source: Journal of Biomechanical Engineering:;2009:;volume( 131 ):;issue: 002:;page 21002
    Author(s): Bumsoo Han; Jeffrey D. Miller; Jun K. Jung
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Freezing of biological tissue is emerging in various biomedical applications. The success of these applications requires precise control of the tissue functionality, which is closely associated ...
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