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Fibril Microstructure Affects Strain Transmission Within Collagen Extracellular Matrices
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The next generation of medical devices and engineered tissues will require development of scaffolds that mimic the structural and functional properties of the extracellular matrix (ECM) component ...
Local, Three-Dimensional Strain Measurements Within Largely Deformed Extracellular Matrix Constructs
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The ability to create extracellular matrix (ECM) constructs that are mechanically and biochemically similar to those found in vivo and to understand how their properties affect cellular responses ...
Self-sealing, Large Bore Arterial Punctures: A Counterintuitive New Phenomenon
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The human femoral artery can bleed dangerously following the removal of a catheter during cardiac catheterization. In this study, a modified technique of needle insertion, simply inserting the ...
Tensile Mechanical Properties of Three-Dimensional Type I Collagen Extracellular Matrices With Varied Microstructure
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The importance and priority of specific micro-structural and mechanical design parameters must be established to effectively engineer scaffolds (biomaterials) that mimic the extracellular matrix ...