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    A Surface-to-Surface Finite Element Algorithm for Large Deformation Frictional Contact in febio 

    Source: Journal of Biomechanical Engineering:;2018:;volume( 140 ):;issue: 008:;page 81013
    Author(s): Zimmerman, Brandon K.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: This study formulates a finite element algorithm for frictional contact of solid materials, accommodating finite deformation and sliding. The algorithm uses a penalty method regularized with an augmented Lagrangian scheme ...
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    Continuum Thermodynamics of Constrained Reactive Mixtures 

    Source: Journal of Biomechanical Engineering:;2021:;volume( 144 ):;issue: 004:;page 41011-1
    Author(s): Ateshian, Gerard A.; Zimmerman, Brandon K.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Mixture theory models continua consisting of multiple constituents with independent motions. In constrained mixtures, all constituents share the same velocity but they may have different reference configurations. The theory ...
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    Continuum Growth Mechanics: Reconciling Two Common Frameworks 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 010:;page 101003-1
    Author(s): Ateshian, Gerard A.; LaBelle, Steven A.; Weiss, Jeffrey A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The objective of this study was to investigate whether the two most common growth mechanics modeling frameworks, the constrained-mixture growth model and the kinematic growth model, could be reconciled mathematically. The ...
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    Multiphasic Finite Element Framework for Modeling Hydrated Mixtures With Multiple Neutral and Charged Solutes 

    Source: Journal of Biomechanical Engineering:;2013:;volume( 135 ):;issue: 011:;page 111001
    Author(s): Ateshian, Gerard A.; Maas, Steve; Weiss, Jeffrey A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Computational tools are often needed to model the complex behavior of biological tissues and cells when they are represented as mixtures of multiple neutral or charged constituents. This study presents the formulation of ...
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    Finite Element Prediction of Transchondral Stress and Strain in the Human Hip 

    Source: Journal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 002:;page 21021
    Author(s): Henak, Corinne R.; Ateshian, Gerard A.; Weiss, Jeffrey A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Cartilage fissures, surface fibrillation, and delamination represent early signs of hip osteoarthritis (OA). This damage may be caused by elevated first principal (most tensile) strain and maximum shear stress. The objectives ...
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    Modeling Pulse Wave Propagation Through a Stenotic Artery With Fluid Structure Interaction: A Validation Study Using Ultrasound Pulse Wave Imaging 

    Source: Journal of Biomechanical Engineering:;2020:;volume( 143 ):;issue: 003:;page 031005-1
    Author(s): Gatti, Vittorio; Nauleau, Pierre; Karageorgos, Grigorios M.; Shim, Jay J.; Ateshian, Gerard A.; Konofagou, Elisa E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Pulse wave imaging (PWI) is an ultrasound-based method that allows spatiotemporal mapping of the arterial pulse wave propagation, from which the local pulse wave velocity (PWV) can be derived. Recent reports indicate that ...
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    Direct Osmotic Pressure Measurements in Articular Cartilage Demonstrate Nonideal and Concentration-Dependent Phenomena 

    Source: Journal of Biomechanical Engineering:;2020:;volume( 143 ):;issue: 004:;page 041007-1
    Author(s): Zimmerman, Brandon K.; Nims, Robert J.; Chen, Alex; Hung, Clark T.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The osmotic pressure in articular cartilage serves an important mechanical function in healthy tissue. Its magnitude is thought to play a role in advancing osteoarthritis. The aims of this study were to: (1) isolate and ...
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    Finite Element Implementation of Biphasic-Fluid Structure Interactions in febio 

    Source: Journal of Biomechanical Engineering:;2021:;volume( 143 ):;issue: 009:;page 091005-1
    Author(s): Shim, Jay J.; Maas, Steve A.; Weiss, Jeffrey A.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In biomechanics, solid–fluid mixtures have commonly been used to model the response of hydrated biological tissues. In cartilage mechanics, this type of mixture, where the fluid and solid constituents are both assumed to ...
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    Modeling Fatigue Failure of Cartilage and Fibrous Biological Tissues Using Constrained Reactive Mixture Theory 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 012:;page 121001-1
    Author(s): Zimmerman, Brandon K.; Maas, Steve A.; Weiss, Jeffrey A.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Fatigue failure in biological soft tissues plays a critical role in the etiology of chronic soft tissue injuries and diseases such as osteoarthritis (OA). Understanding failure mechanisms is hindered by the decades-long ...
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    Finite Element Implementation of Computational Fluid Dynamics With Reactive Neutral and Charged Solute Transport in FEBio 

    Source: Journal of Biomechanical Engineering:;2023:;volume( 145 ):;issue: 009:;page 91011-1
    Author(s): Shim, Jay J.; Maas, Steve A.; Weiss, Jeffrey A.; Ateshian, Gerard A.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The objective of this study was to implement a novel fluid-solutes solver into the open-source finite element software FEBio, that extended available modeling capabilities for biological fluids and fluid-solute mixtures. ...
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