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    Blood Flow Manipulation in the Aorta With Coarctation and Arch Narrowing for Pediatric Subjects

    Source: Journal of Applied Mechanics:;2020:;volume( 088 ):;issue: 002::page 021001-1
    Author:
    Jia, Yuxi
    ,
    Punithakumar, Kumaradevan
    ,
    Noga, Michelle
    ,
    Hemmati, Arman
    DOI: 10.1115/1.4048570
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The characteristics of blood flow in an abnormal pediatric aorta with an aortic coarctation and aortic arch narrowing are examined using direct numerical simulations and patient-specific boundary conditions. The blood flow simulations of a normal pediatric aorta are used for comparison to identify unique flow features resulting from the aorta geometrical anomalies. Despite flow similarities compared to the flow in normal aortic arch, the flow velocity decreases with an increase in pressure, wall shear stress, and vorticity around both anomalies. The presence of wall shear stresses in the trailing indentation region and aorta coarctation opposing the primary flow direction suggests that there exist recirculation zones in the aorta. The discrepancy in relative flowrates through the top and bottom of the aorta outlets, and the pressure drop across the coarctation, implies a high blood pressure in the upper body and a low blood pressure in the lower body. We propose using flow manipulators prior to the aortic arch and coarctation to lower the wall shear stress, while making the recirculation regions both smaller and weaker. The flow manipulators form a guide to divert and correct blood flow in critical regions of the aorta with anomalies.
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      Blood Flow Manipulation in the Aorta With Coarctation and Arch Narrowing for Pediatric Subjects

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    https://yetl.yabesh.ir/yetl1/handle/yetl/4277605
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    contributor authorJia, Yuxi
    contributor authorPunithakumar, Kumaradevan
    contributor authorNoga, Michelle
    contributor authorHemmati, Arman
    date accessioned2022-02-05T22:28:46Z
    date available2022-02-05T22:28:46Z
    date copyright11/3/2020 12:00:00 AM
    date issued2020
    identifier issn0021-8936
    identifier otherjam_88_2_021001.pdf
    identifier urihttp://yetl.yabesh.ir/yetl1/handle/yetl/4277605
    description abstractThe characteristics of blood flow in an abnormal pediatric aorta with an aortic coarctation and aortic arch narrowing are examined using direct numerical simulations and patient-specific boundary conditions. The blood flow simulations of a normal pediatric aorta are used for comparison to identify unique flow features resulting from the aorta geometrical anomalies. Despite flow similarities compared to the flow in normal aortic arch, the flow velocity decreases with an increase in pressure, wall shear stress, and vorticity around both anomalies. The presence of wall shear stresses in the trailing indentation region and aorta coarctation opposing the primary flow direction suggests that there exist recirculation zones in the aorta. The discrepancy in relative flowrates through the top and bottom of the aorta outlets, and the pressure drop across the coarctation, implies a high blood pressure in the upper body and a low blood pressure in the lower body. We propose using flow manipulators prior to the aortic arch and coarctation to lower the wall shear stress, while making the recirculation regions both smaller and weaker. The flow manipulators form a guide to divert and correct blood flow in critical regions of the aorta with anomalies.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleBlood Flow Manipulation in the Aorta With Coarctation and Arch Narrowing for Pediatric Subjects
    typeJournal Paper
    journal volume88
    journal issue2
    journal titleJournal of Applied Mechanics
    identifier doi10.1115/1.4048570
    journal fristpage021001-1
    journal lastpage021001-13
    page13
    treeJournal of Applied Mechanics:;2020:;volume( 088 ):;issue: 002
    contenttypeFulltext
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