Journal of Engineering and Science in Medical Diagnostics and Therapy: Recent submissions
Now showing items 301-316 of 316
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Transition From Phasic to Tonic Contractility in Airway Smooth Muscle After Birth: An Experimental and Computational Modeling Study
(The American Society of Mechanical Engineers (ASME), 2019)Fetal airway smooth muscle (ASM) exhibits phasic contractile behavior, which transitions to a more sustained “tonic” contraction after birth. The timing and underlying mechanisms of ASM transition from a phasic to a tonic ... -
Design of a Novel Electrode of Radiofrequency Ablation for Large Tumors: A Finite Element Study
(The American Society of Mechanical Engineers (ASME), 2019)The aim of the study was to design a novel radiofrequency (RF) electrode for larger and rounder ablation volumes and its ability to achieve the complete ablation of liver tumors larger than 3 cm in diameter using finite ... -
Ultrasound Transducers for Biomedical Imaging and Therapy
(The American Society of Mechanical Engineers (ASME), 2019) -
Saponins of Dioscorea Nipponicae Inhibits IL-17A-Induced Changes in Biomechanical Behaviors of In Vitro Cultured Human Airway Smooth Muscle Cells
(The American Society of Mechanical Engineers (ASME), 2019)Airway hyperresponsiveness (AHR) is one of the main pathologic features of bronchial asthma, which is largely attributable to enhanced contractile response of asthmatic airway smooth muscle. Although β2 adrenergic receptor ... -
Editorial
(The American Society of Mechanical Engineers (ASME), 2019) -
The Aftermath of Bronchoconstriction
(The American Society of Mechanical Engineers (ASME), 2019)Asthma is characterized by chronic airway inflammation, airway remodeling, and excessive constriction of the airway. Detailed investigation exploring inflammation and the role of immune cells has revealed a variety of ... -
Acoustic Signatures of Left Ventricular Assist Device Thrombosis
(The American Society of Mechanical Engineers (ASME), 2019)Left ventricular assist devices (LVADs) are life-saving, surgically implanted mechanical heart pumps used to treat patients with advanced heart failure (HF). While life-saving, LVAD support is associated with a high incidence ... -
Plastic Energy Dissipation in Lumbar Spine Implants: A Contact Mechanics Point of View
(The American Society of Mechanical Engineers (ASME), 2019)In this study, an elastoplastic contact model is developed for L1–L5 lumbar spine implants. Roughness effect is included to estimate energy loss which is an indication of wear and subsequently the issue of metal debris in ... -
Effect of Tumor Volume on Drug Delivery in Heterogeneous Vasculature of Human Brain Tumors
(The American Society of Mechanical Engineers (ASME), 2019)Drug distribution in tumors is strongly dependent on tumor biological properties such as tumor volume, vasculature, and porosity. An understanding of the drug distribution pattern in tumors can help in enhancing the ... -
A Computationally Efficient Computer-Aided Design Strategy for Iterative Combat Helmet Design and Analysis
(The American Society of Mechanical Engineers (ASME), 2019)Assessing combat helmet ballistic performance is a costly endeavor using either an experimental or a computational process. Experimental assessment requires many iterations and helmets to acquire a sufficient data set. To ... -
Modeling Decision Support System for Optimal Disease Diagnosis and Treatment of Cerebral Aneurysm
(The American Society of Mechanical Engineers (ASME), 2019)This paper presents a novel decision support system (DSS) to assist medics administer optimal clinical diagnosis and effective healthcare post-treatment solutions. The DSS model that evolved from the research work predicted ... -
A Micromachined Pb(Mg1/3Nb2/3)O3-PbTiO3 Single Crystal Composite Circular Array for Intravascular Ultrasound Imaging
(The American Society of Mechanical Engineers (ASME), 2019)This paper describes the design, fabrication, and characterization of a micromachined high-frequency Pb(Mg1/3Nb2/3)O3-PbTiO3 (PMN-PT) single crystal/epoxy 1–3 composite ultrasound circular array. The 1–3 composites were ... -
The Role of Airway Shunt Elastance on the Compartmentalization of Respiratory System Impedance
(The American Society of Mechanical Engineers (ASME), 2019)An inverse model consisting of two elastic compartments connected in series and served by two airway conduits has recently been fit to measurements of respiratory impedance in obese subjects. Increases in the resistance ... -
The Strain on Airway Smooth Muscle During a Deep Inspiration to Total Lung Capacity
(The American Society of Mechanical Engineers (ASME), 2019)The deep inspiration (DI) maneuver entices a great deal of interest because of its ability to temporarily ease the flow of air into the lungs. This salutary effect of a DI is proposed to be mediated, at least partially, ... -
Reorganization of the Vimentin Network in Smooth Muscle
(The American Society of Mechanical Engineers (ASME), 2019)Vimentin intermediate filaments (IFs) link to desmosomes (intercellular junctions) on the membrane and dense bodies in the cytoplasm, which provides a structural base for intercellular and intracellular force transmission ... -
Special Issue: Under the Hood—A Look at the Mechanisms Regulating Lung Function
(The American Society of Mechanical Engineers (ASME), 2019)