Journal of Engineering and Science in Medical Diagnostics and Therapy: Recent submissions
Now showing items 281-300 of 316
-
An Analytical Model of Tumors With Higher Permeability Than Surrounding Tissues for Ultrasound Elastography Imaging
(The American Society of Mechanical Engineers (ASME), 2019)Cancerous tissues are known to possess different poroelastic properties with respect to normal tissues. Interstitial permeability is one of these properties, and it has been shown to be of diagnostic relevance for the ... -
Mechanobiology in Medical Diagnostics and Therapy
(The American Society of Mechanical Engineers (ASME), 2019) -
Evaluation of the Laser-Induced Thermotherapy Treatment Effect of Breast Cancer Based on Tissue Viscoelastic Properties
(The American Society of Mechanical Engineers (ASME), 2019)Photothermal therapy (PTT) has been emerging as an effective, minimally invasive approach to treat cancers. However, a method to quantitatively evaluate the treatment effect after laser-induced thermotherapy (LITT) is ... -
Quantification of Left Ventricular Shape Differentiates Pediatric Pulmonary Hypertension Subjects From Matched Controls
(The American Society of Mechanical Engineers (ASME), 2019)Changes in left ventricle (LV) shape are observed in patients with pulmonary hypertension (PH). Quantification of ventricular shape could serve as a tool to noninvasively monitor pediatric patients with PH. Decomposing the ... -
Novel Imaging Technologies in Laparoscopic Gynecologic Surgery: A Systematic Review
(The American Society of Mechanical Engineers (ASME), 2019)Novel imaging technologies continued to be introduced into the operative setting. In particular, novel image-enhanced laparoscopic techniques are being explored for use in gynecologic operations. This systematic review ... -
Damage Accumulation Modeling and Rate Dependency of Spinal Dura Mater
(The American Society of Mechanical Engineers (ASME), 2019)As the strongest of the meningeal tissues, the spinal dura mater plays an important role in the overall behavior of the spinal cord-meningeal complex (SCM). It follows that the accumulation of damage affects the dura mater's ... -
Particulate Deposition in a Patient With Tracheal Stenosis
(The American Society of Mechanical Engineers (ASME), 2019)The presence of obstructions such as tracheal stenosis has important effects on respiratory functions. Tracheal stenosis impacts the therapeutic efficacy of inhaled medications as a result of alterations in particle transport ... -
Ultrasound Shear Wave Elastography of the Elbow Ulnar Collateral Ligament: Reliability Test and a Preliminary Case Study in a Baseball Pitcher
(The American Society of Mechanical Engineers (ASME), 2019)Overhead throwing athletes are at high risk of the elbow ulnar collateral ligament (UCL) injury, and there is a need for clinical tools to objectively diagnose severity of injury and monitor recovery. Mechanical properties ... -
An In Vitro Experimental Study of the Pulse Delivery Method in Irreversible Electroporation
(The American Society of Mechanical Engineers (ASME), 2019)The purpose of this study was to investigate the feasibility of generating larger ablation volumes using the pulse delivery method in irreversible electroporation (IRE) using a potato model. Ten types of pulse timing schemes ... -
Assessment of 11 Available Materials With Custom Three-Dimensional-Printing Patterns for the Simulation of Muscle, Fat, and Lung Hounsfield Units in Patient-Specific Phantoms
(The American Society of Mechanical Engineers (ASME), 2019)A couple of fused deposition modeling (FDM) three-dimensional (3D) printers using variable infill density patterns were employed to simulate human muscle, fat, and lung tissue as it is represented by Hounsfield units (HUs) ... -
Evaluating Changes in Shear Modulus of Elbow Ulnar Collateral Ligament in Overhead Throwing Athletes Over the Course of a Competitive Season
(The American Society of Mechanical Engineers (ASME), 2019)The anterior band of the ulnar collateral ligament (UCL) is commonly subjected to repetitive stress in overhead-throwing athletes, causing high subfailure strain and change in mechanical properties of the ligament. ... -
Level of Cutaneous Blood Flow Depression During Cryotherapy Depends on Applied Temperature: Criteria for Protocol Design
(The American Society of Mechanical Engineers (ASME), 2019)Cryotherapy is commonly used for the management of soft tissue injury. The dose effect of the applied cooling temperature has not been quantified previously. Six subjects were exposed during five different experiments to ... -
Generation and Thermal Simulation of a Digital Model of the Female Breast in Prone Position
(The American Society of Mechanical Engineers (ASME), 2019)Infrared (IR) breast thermography has been associated with the early detection of breast cancer (BC). However, findings in previous studies have been inconclusive. The upright position of subjects during imaging introduces ... -
Determination of the Structural Elasticity of Human Fingernails by Bending Test and Comparison with the Structural Elasticity of Human Hair
(The American Society of Mechanical Engineers (ASME), 2019)A bending test scheme for accurately determining the structural elasticity of human nails is reported. The structural elasticity expresses the deformability of a multi-layered material for bending, and it is the flexural ... -
Quantification of Thermal Injury to the Healthy Tissue Due to Imperfect Electrode Placements During Radiofrequency Ablation of Breast Tumor
(The American Society of Mechanical Engineers (ASME), 2019)Radiofrequency ablation (RFA) has emerged as an alternative treatment modality for treating various tumors with minimum intervention. The application of RFA in treating breast tumor is still in its infancy stage. Nevertheless, ... -
Molecular Mechanisms for the Mechanical Modulation of Airway Responsiveness
(The American Society of Mechanical Engineers (ASME), 2019)The smooth muscle of the airways is exposed to continuously changing mechanical forces during normal breathing. The mechanical oscillations that occur during breathing have profound effects on airway tone and airway ... -
Parametric study of the design variables of an arborizing catheter on dispersal volume using a biphasic computational model
(The American Society of Mechanical Engineers (ASME), 2019)Convection enhanced delivery (CED) is an investigational therapy developed to circumvent the limitations of drug delivery to the brain. Catheters are used in CED to locally infuse therapeutic agents into brain tissue. CED ... -
Airway Transmural Pressures in an Airway Tree During Bronchoconstriction in Asthma
(The American Society of Mechanical Engineers (ASME), 2019)Airway transmural pressure in healthy homogeneous lungs with dilated airways is approximately equal to the difference between intraluminal and pleural pressure. However, bronchoconstriction causes airway narrowing, parenchymal ... -
Mechanopharmacology and Synergistic Relaxation of Airway Smooth Muscle
(The American Society of Mechanical Engineers (ASME), 2019)Asthmatic airways are stiffer than normal. We have shown that the cytoskeletal passive stiffness of airway smooth muscle (ASM) can be regulated by intracellular signaling pathways, especially those associated with Rho ... -
Myosin Crossbridge, Contractile Unit, and the Mechanism of Contraction in Airway Smooth Muscle: A Mechanical Engineer's Perspective
(The American Society of Mechanical Engineers (ASME), 2019)Muscle contraction is caused by the action of myosin motors within the structural confines of contractile unit arrays. When the force generated by cyclic interactions between myosin crossbridges and actin filaments is ...