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    A New Concept of Needle-Free Jet Injector by the Impact Driven Method

    Source: Journal of Medical Devices:;2017:;volume( 011 ):;issue: 001::page 11011
    Author:
    Mukda, Prachya
    ,
    Pianthong, Kulachate
    ,
    Seehanam, Wirapan
    DOI: 10.1115/1.4035563
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Currently, most of commercial needle-free jet injectors generate the liquid jet by a method called “driving object method” (DOM); however, the reliability and efficiency are still questioned. This paper proposes a new concept of jet generation method, known as “impact driven method” (IDM). A prototype of an IDM jet injector is designed, built, tested, and compared to a commercial device (Cool.click, Tigard, OR). Fundamental characteristics, i.e., the exit jet velocity and impact pressure, are measured. Jet injection processes are visualized both in air and in 20% polyacrylamide by high speed photography. In this study, from the prototype of the IDM jet injector, a maximum jet velocity of 400 m/s and impact peak pressure of 68 MPa can be obtained. It is clear that the IDM jet injector provides a double pulsed liquid jet, which is a major advantage over the commercial jet injector. Because, the first pulse gives a shorter erosion stage, and then, immediately the second pulse follows and provides a better penetration, wider lateral dispersion, and considerably less back splash. Hence, lower pain level and higher delivery efficiency should be achieved. It can be concluded that the IDM concept is highly feasible for implementation in real applications, either for human or animal injection. However, the control and accuracy of IDM still needs to be carefully investigated.
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      A New Concept of Needle-Free Jet Injector by the Impact Driven Method

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    contributor authorMukda, Prachya
    contributor authorPianthong, Kulachate
    contributor authorSeehanam, Wirapan
    date accessioned2017-11-25T07:18:29Z
    date available2017-11-25T07:18:29Z
    date copyright2017/25/1
    date issued2017
    identifier issn1932-6181
    identifier othermed_011_01_011011.pdf
    identifier urihttp://138.201.223.254:8080/yetl1/handle/yetl/4235199
    description abstractCurrently, most of commercial needle-free jet injectors generate the liquid jet by a method called “driving object method” (DOM); however, the reliability and efficiency are still questioned. This paper proposes a new concept of jet generation method, known as “impact driven method” (IDM). A prototype of an IDM jet injector is designed, built, tested, and compared to a commercial device (Cool.click, Tigard, OR). Fundamental characteristics, i.e., the exit jet velocity and impact pressure, are measured. Jet injection processes are visualized both in air and in 20% polyacrylamide by high speed photography. In this study, from the prototype of the IDM jet injector, a maximum jet velocity of 400 m/s and impact peak pressure of 68 MPa can be obtained. It is clear that the IDM jet injector provides a double pulsed liquid jet, which is a major advantage over the commercial jet injector. Because, the first pulse gives a shorter erosion stage, and then, immediately the second pulse follows and provides a better penetration, wider lateral dispersion, and considerably less back splash. Hence, lower pain level and higher delivery efficiency should be achieved. It can be concluded that the IDM concept is highly feasible for implementation in real applications, either for human or animal injection. However, the control and accuracy of IDM still needs to be carefully investigated.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleA New Concept of Needle-Free Jet Injector by the Impact Driven Method
    typeJournal Paper
    journal volume11
    journal issue1
    journal titleJournal of Medical Devices
    identifier doi10.1115/1.4035563
    journal fristpage11011
    journal lastpage011011-10
    treeJournal of Medical Devices:;2017:;volume( 011 ):;issue: 001
    contenttypeFulltext
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    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
    yabeshDSpacePersian