Journal of Biomechanical Engineering: Recent submissions
Now showing items 521-540 of 5302
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Review of the Development of Hemodynamic Modeling Techniques to Capture Flow Behavior in Arteries Affected by Aneurysm, Atherosclerosis, and Stenting
(The American Society of Mechanical Engineers (ASME), 2021)Cardiovascular diseases (CVDs) are the leading cause of death in the developed world. CVD can include atherosclerosis, aneurysm, dissection, or occlusion of the main arteries. Many CVDs are caused by unhealthy hemodynamics. ... -
Models of Shear-Induced Platelet Activation and Numerical Implementation With Computational Fluid Dynamics Approaches
(The American Society of Mechanical Engineers (ASME), 2021)Shear-induced platelet activation is one of the critical outcomes when blood is exposed to elevated shear stress. Excessively activated platelets in the circulation can lead to thrombus formation and platelet consumption, ... -
Optimizing Backrest Geometry to Minimize Interfacial Pressure Concentrations in the Mid-to-Lumbar Region During Leg Press Resistance Training
(The American Society of Mechanical Engineers (ASME), 2022)The leg press is a resistance training (RT) exercise common to both weight- and powerlifting, where spine-related injuries remain prevalent. Here, the elevated loading has the potential to result in increased pressure on ... -
Effect of Temperature and Freezing on Human Adipose Tissue Material Properties Characterized by High-Rate Indentation: Puncture Testing
(The American Society of Mechanical Engineers (ASME), 2021)The characterization of human subcutaneous adipose tissue (SAT) under high-rate loading is valuable for development of biofidelic finite element human body models (FE-HBMs) to predict seat belt-pelvis interaction and injury ... -
An Efficient One-Step Moment Balancing Algorithm for Computing Medial and Lateral Knee Compartment Contact Forces
(The American Society of Mechanical Engineers (ASME), 2021)The knee adduction moment is associated with the progression of knee osteoarthritis (OA). The adduction moment reflects the net effect of muscles, passive tissues and bone-on-bone contact forces. Medial compartment OA is ... -
Computational Modeling of Aortic Stenosis With a Reduced Degree-of-Freedom Fluid-Structure Interaction Valve Model
(The American Society of Mechanical Engineers (ASME), 2021)In this study, a novel reduced degree-of-freedom (rDOF) aortic valve model is employed to investigate the fluid-structure interaction (FSI) and hemodynamics associated with aortic stenosis. The dynamics of the valve leaflets ... -
Electromyography-Assisted Neuromusculoskeletal Models Can Estimate Physiological Muscle Activations and Joint Moments Across the Neck Before Impacts
(The American Society of Mechanical Engineers (ASME), 2021)Knowledge of neck muscle activation strategies before sporting impacts is crucial for investigating mechanisms of severe spinal injuries. However, measurement of muscle activations during impacts is experimentally challenging ... -
Scale-Resolving Simulations of Steady and Pulsatile Flow Through Healthy and Stenotic Heart Valves
(The American Society of Mechanical Engineers (ASME), 2021)Blood-flow downstream of stenotic and healthy aortic valves exhibits intermittent random fluctuations in the velocity field which are associated with turbulence. Such flows warrant the use of computationally demanding ... -
Model Based Design of a Low Cost and Compliant Low Profile Prosthetic Foot
(The American Society of Mechanical Engineers (ASME), 2021)This paper describes the design of a simple and low-cost compliant low-profile prosthetic foot based on a cantilevered beam of uniform strength. The prosthetic foot is developed such that the maximum stress experienced by ... -
Transition to Turbulence Downstream of a Stenosis for Whole Blood and a Newtonian Analog Under Steady Flow Conditions
(The American Society of Mechanical Engineers (ASME), 2021)Blood, a multiphase fluid comprised of plasma, blood cells, and platelets, is known to exhibit a shear-thinning behavior at low shear rates and near-Newtonian behavior at higher shear rates. However, less is known about ... -
Simplified Mechanical Tests Can Simulate Physiological Mechanics of a Fixation Construct for Periprosthetic Femoral Fractures
(The American Society of Mechanical Engineers (ASME), 2021)Plate fractures after fixation of a Vancouver Type B1 periprosthetic femoral fracture (PFF) are difficult to treat and could lead to severe disability. However, due to the lack of direct measurement of in vivo performance ... -
A Transmural Path Model Improves the Definition of the Orthotropic Tissue Structure in Heart Simulations
(The American Society of Mechanical Engineers (ASME), 2021)In the past decades, the structure of the heart, human as well as other species, has been explored in a detailed way, e.g., via histological studies or diffusion tensor magnetic resonance imaging. Nevertheless, the assignment ... -
Development and Validation of a Finite Element Model of Wear in UHMWPE Liner Using Experimental Data From Hip Simulator Studies
(The American Society of Mechanical Engineers (ASME), 2021)The wear of acetabular liner is one of the key factors determining osseointegration and long-term performance of total hip joint replacement implants. The experimental measurements of wear in total hip replacement components ... -
Collagen Fibril Orientation in Tissue Specimens From Atherosclerotic Plaque Explored Using Small Angle X-Ray Scattering
(The American Society of Mechanical Engineers (ASME), 2021)Atherosclerotic plaques can gradually develop in certain arteries. Disruption of fibrous tissue in plaques can result in plaque rupture and thromboembolism, leading to heart attacks and strokes. Collagen fibrils are important ... -
Previously Unrecognized Source of Error in the Change in Maximum Total Point Motion to Determine Continuous Migration of Unstable Tibial Baseplates
(The American Society of Mechanical Engineers (ASME), 2021)In radiostereometric analysis (RSA), continuous migration denoted as ΔMTPM is the difference between maximum total point motion (MTPM) at 2 years relative to time zero and MTPM at 1 year relative to time zero. Continuous ... -
In Vitro Flow Chamber Design for the Study of Endothelial Cell (Patho)Physiology
(The American Society of Mechanical Engineers (ASME), 2021)In the native vasculature, flowing blood produces a frictional force on vessel walls that affects endothelial cell function and phenotype. In the arterial system, the vasculature's local geometry directly influences ... -
A Bioreactor for Controlled Electrical and Mechanical Stimulation of Developing Scaffold-Free Constructs
(The American Society of Mechanical Engineers (ASME), 2022)Bioreactors are commonly used to apply biophysically relevant stimulations to tissue-engineered constructs in order to explore how these stimuli influence tissue development, healing, and homeostasis, and they offer great ... -
A New Method for Quantifying Abdominal Aortic Wall Shear Stress Using Phase Contrast Magnetic Resonance Imaging and the Womersley Solution
(The American Society of Mechanical Engineers (ASME), 2022)Wall shear stress (WSS) is an important mediator of cardiovascular pathologies and there is a need for its reliable evaluation as a potential prognostic indicator. The purpose of this work was to develop a method that ... -
Quantification of Behind Shield Blunt Impacts Using a Modified Upper Extremity Anthropomorphic Test Device
(The American Society of Mechanical Engineers (ASME), 2022)Ballistic shields are used by military and police members in dangerous situations to protect the user against threats such as gunfire. When struck, the shield material deforms to absorb the incoming kinetic energy of the ... -
A Noninvasive Assessment of Flow Based on Contrast Dispersion in Computed Tomography Angiography: A Computational and Experimental Phantom Study
(The American Society of Mechanical Engineers (ASME), 2022)Transluminal attenuation gradient (TAG), defined as the gradient of the contrast agent attenuation drop along the vessel, is an imaging biomarker that indicates stenosis in the coronary arteries. The transluminal attenuation ...