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    Cells on Porous Substrates In Vitro and In Vivo

    Source: Journal of Engineering Materials and Technology:;1974:;volume( 096 ):;issue: 002::page 131
    Author:
    K. D. Ansevin
    ,
    C. A. Homsy
    ,
    B. V. Lipps
    ,
    H. G. Welgus
    DOI: 10.1115/1.3443195
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Disaggregated cells of kidney, lung and liver of 14-day-old chick embryos were cultivated in vitro on several open-pore, organic-polymer sponges and on one gelatin sponge; in some cases this was followed by short-term, subcutaneous implantation into rats. In order to study invasion of connective tissue cells into the porous matrix, the same organic-polymer materials were implanted into rats, and in one experimental series this was followed by in vitro cultivation after they had been retrieved from the animals. The results showed that: 1) epithelial cells have different requirements for invasion and histogenesis from those of connective tissue cells; 2) the type of porous substrate influences morphology of connective tissue that forms within it.
    keyword(s): Gelatin , Biological tissues , Polymers , Kidney , Liver AND Lung ,
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      Cells on Porous Substrates In Vitro and In Vivo

    URI
    https://yetl.yabesh.ir/yetl1/handle/yetl/164829
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    contributor authorK. D. Ansevin
    contributor authorC. A. Homsy
    contributor authorB. V. Lipps
    contributor authorH. G. Welgus
    date accessioned2017-05-09T01:38:14Z
    date available2017-05-09T01:38:14Z
    date copyrightApril, 1974
    date issued1974
    identifier issn0094-4289
    identifier otherJEMTA8-26836#131_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/164829
    description abstractDisaggregated cells of kidney, lung and liver of 14-day-old chick embryos were cultivated in vitro on several open-pore, organic-polymer sponges and on one gelatin sponge; in some cases this was followed by short-term, subcutaneous implantation into rats. In order to study invasion of connective tissue cells into the porous matrix, the same organic-polymer materials were implanted into rats, and in one experimental series this was followed by in vitro cultivation after they had been retrieved from the animals. The results showed that: 1) epithelial cells have different requirements for invasion and histogenesis from those of connective tissue cells; 2) the type of porous substrate influences morphology of connective tissue that forms within it.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleCells on Porous Substrates In Vitro and In Vivo
    typeJournal Paper
    journal volume96
    journal issue2
    journal titleJournal of Engineering Materials and Technology
    identifier doi10.1115/1.3443195
    journal fristpage131
    journal lastpage137
    identifier eissn1528-8889
    keywordsGelatin
    keywordsBiological tissues
    keywordsPolymers
    keywordsKidney
    keywordsLiver AND Lung
    treeJournal of Engineering Materials and Technology:;1974:;volume( 096 ):;issue: 002
    contenttypeFulltext
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    DSpace software copyright © 2002-2015  DuraSpace
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