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    Bone Resorption Induced by Fluid Flow

    Source: Journal of Biomechanical Engineering:;2009:;volume( 131 ):;issue: 009::page 94505
    Author:
    Lars Johansson
    ,
    Anna Fahlgren
    ,
    Per Aspenberg
    ,
    Ulf Edlund
    DOI: 10.1115/1.3194756
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: A model where bone resorption is driven by stimulus from fluid flow is developed and used as a basis for computer simulations, which are compared with experiments. Models for bone remodeling are usually based on the state of stress, strain, or energy density of the bone tissue as the stimulus for remodeling. We believe that there is experimental support for an additional pathway, where an increase in the amount of osteoclasts, and thus osteolysis, is caused by the time history of fluid flow velocity, fluid pressure, or other parameters related to fluid flow at the bone/soft tissue interface of the porosities in the bone.
    keyword(s): Fluid dynamics , Flow (Dynamics) , Bone , Soft tissues , Porosity AND Equations ,
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      Bone Resorption Induced by Fluid Flow

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    https://yetl.yabesh.ir/yetl1/handle/yetl/139868
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    • Journal of Biomechanical Engineering

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    contributor authorLars Johansson
    contributor authorAnna Fahlgren
    contributor authorPer Aspenberg
    contributor authorUlf Edlund
    date accessioned2017-05-09T00:31:32Z
    date available2017-05-09T00:31:32Z
    date copyrightSeptember, 2009
    date issued2009
    identifier issn0148-0731
    identifier otherJBENDY-27031#094505_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/139868
    description abstractA model where bone resorption is driven by stimulus from fluid flow is developed and used as a basis for computer simulations, which are compared with experiments. Models for bone remodeling are usually based on the state of stress, strain, or energy density of the bone tissue as the stimulus for remodeling. We believe that there is experimental support for an additional pathway, where an increase in the amount of osteoclasts, and thus osteolysis, is caused by the time history of fluid flow velocity, fluid pressure, or other parameters related to fluid flow at the bone/soft tissue interface of the porosities in the bone.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleBone Resorption Induced by Fluid Flow
    typeJournal Paper
    journal volume131
    journal issue9
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.3194756
    journal fristpage94505
    identifier eissn1528-8951
    keywordsFluid dynamics
    keywordsFlow (Dynamics)
    keywordsBone
    keywordsSoft tissues
    keywordsPorosity AND Equations
    treeJournal of Biomechanical Engineering:;2009:;volume( 131 ):;issue: 009
    contenttypeFulltext
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