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    The Influence of Axial Compression on the Cellular and Mechanical Function of Spinal Tissues; Emphasis on the Nucleus Pulposus and Annulus Fibrosus: A Review 

    Source: Journal of Biomechanical Engineering:;2021:;volume( 143 ):;issue: 005:;page 050802-1
    Author(s): McMorran, John G.; Gregory, Diane E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In light of the correlation between chronic back pain and intervertebral disc (IVD) degeneration, this literature review seeks to illustrate the importance of the hydraulic response across the nucleus pulposus (NP)-annulus ...
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    An Examination of the Influence of Strain Rate on Subfailure Mechanical Properties of the Annulus Fibrosus 

    Source: Journal of Biomechanical Engineering:;2010:;volume( 132 ):;issue: 009:;page 91010
    Author(s): Diane E. Gregory; Jack P. Callaghan
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Disk herniation is often considered a cumulative injury in that repetitive stress on the posterior annulus can result in the nucleus pulposus penetrating the annulus fibrosus and eventually ...
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    A Comparison of Uniaxial and Biaxial Mechanical Properties of the Annulus Fibrosus: A Porcine Model 

    Source: Journal of Biomechanical Engineering:;2011:;volume( 133 ):;issue: 002:;page 24503
    Author(s): Diane E. Gregory; Jack P. Callaghan
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The annulus fibrosus of the intervertebral disk experiences multidirectional tension in vivo, yet the majority of mechanical property testing has been uniaxial. Therefore, our understanding of how ...
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    A Novel Testing Method to Quantify Mechanical Properties of the Intact Annulus Fibrosus Ring From Rat-Tail Intervertebral Discs 

    Source: Journal of Biomechanical Engineering:;2022:;volume( 144 ):;issue: 011:;page 114503-1
    Author(s): Sinopoli; Sabrina I.;Gregory; Diane E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The annulus fibrosus is the ring-like exterior of the intervertebral disc, which is composed of concentrically organized layers of collagen fiber bundles. The mechanical properties of the annulus have been studied extensively; ...
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    A New Neighborhood Function for Discrete Manufacturing Process Design Optimization Using Generalized Hill Climbing Algorithms 

    Source: Journal of Mechanical Design:;2000:;volume( 122 ):;issue: 002:;page 164
    Author(s): Diane E. Vaughan; Sheldon H. Jacobson; Derek E. Armstrong
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Discrete manufacturing process design optimization can be difficult, due to the large number of manufacturing process design sequences and associated input parameter setting combinations that exist. ...
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    How Static and Cyclic Loading Affect the Mechanical Properties of the Porcine Annulus Fibrosus 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 011:;page 114503-1
    Author(s): Neptune, Andra; McMorran, John G.; Gregory, Diane E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: This study sought to evaluate the effects of prolonged cyclic loading on the tissue-level mechanical properties of the spinal annulus fibrosus. Functional spinal units (FSUs) were obtained from porcine cervical spines at ...
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    Unloaded Organ Culturing Has a Detrimental Effect on the Axial Mechanical Properties of the Intervertebral Disc 

    Source: Journal of Biomechanical Engineering:;2021:;volume( 143 ):;issue: 008:;page 084501-1
    Author(s): Zwambag, Derek P.; Laird, Brigitte N.; DeWitte-Orr, Stephanie J.; Gregory, Diane E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Healthy function of intervertebral discs (IVDs) depends on their tissue mechanical properties. Native cells embedded within IVD tissues are responsible for building, maintaining, and repairing IVD structures in response ...
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    Does Annulus Fibrosus Lamellar Adhesion Testing Require Preconditioning? 

    Source: Journal of Biomechanical Engineering:;2025:;volume( 147 ):;issue: 002:;page 24502-1
    Author(s): Sinopoli, Sabrina I.; Whittal, Mitchel C.; Briar, K. Josh; Gregory, Diane E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The interlamellar matrix (ILM), located between the annular layers of the intervertebral disc (IVD), is an adhesive component which acts to resist delamination. Investigating the mechanical properties of the ILM can provide ...
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    How Spinal Flexion Influences Fracture Morphology in the Porcine Spine 

    Source: Journal of Biomechanical Engineering:;2026:;volume( 148 ):;issue:001:;page 231
    Author(s): Abuani, Safiya; Platnick, Sofia; Chow, Noah; Sinopoli, Sabrina I.; Gregory, Diane E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Abstract. Acute injuries to the spine, including slips and falls and motor vehicle accidents, most commonly occur when the spine is positioned in flexion. Therefore, the purpose of this study was to investigate how spine ...
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    Precipitation Uncertainty and Raingauge Network Design within Folsom Lake Watershed 

    Source: Journal of Hydrologic Engineering:;2002:;Volume ( 007 ):;issue: 002
    Author(s): Dimitris Tsintikidis; Konstantine P. Georgakakos; Jason A. Sperfslage; Diane E. Smith; Theresa M. Carpenter
    Publisher: American Society of Civil Engineers
    Abstract: The present study examines the estimation of hourly precipitation over the Folsom Lake watershed in mountainous California. The objectives are to (1) quantify the uncertainty associated with the estimation of precipitation ...
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