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contributor authorJ. Peace
contributor authorD. Daniel
contributor authorN. Nirmalakhandan
contributor authorE. Egemen
date accessioned2017-05-08T21:20:22Z
date available2017-05-08T21:20:22Z
date copyrightApril 1997
date issued1997
identifier other%28asce%290733-9372%281997%29123%3A4%28329%29.pdf
identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/47575
description abstractThree schemes proposed in the literature for analyzing joint toxic effects of multicomponent mixtures on fish, namely the additivity index (AI), the mixture toxicity index (MTI), and the similarity parameter (λ) are evaluated in this study for microbial toxicity. A new approach is proposed to establish acceptance limits for the similarity parameter, λ, based on experimental errors and uncertainties. Quantitative structure activity relationship (QSAR) techniques are then used to develop a model to predict the concentrations of components in mixtures that would jointly cause 50% inhibition of microbial respiration. The application of this approach is demonstrated on the experimental toxicity data of six eight-component organic chemical mixtures on microorganisms.
publisherAmerican Society of Civil Engineers
titlePredicting Microbial Toxicity of Nonuniform Multicomponent Mixtures of Organic Chemicals
typeJournal Paper
journal volume123
journal issue4
journal titleJournal of Environmental Engineering
identifier doi10.1061/(ASCE)0733-9372(1997)123:4(329)
treeJournal of Environmental Engineering:;1997:;Volume ( 123 ):;issue: 004
contenttypeFulltext


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