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RISReduced Biaxial Contractility in the Descending Thoracic Aorta of Fibulin 5 Deficient Mice
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The precise role of smooth muscle cell contractility in elastic arteries remains unclear, but accumulating evidence suggests that smooth muscle dysfunction plays an important role in the development of thoracic aortic ...
Decreased Elastic Energy Storage, Not Increased Material Stiffness, Characterizes Central Artery Dysfunction in Fibulin 5 Deficiency Independent of Sex
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Central artery stiffness has emerged over the past 15 years as a clinically significant indicator of cardiovascular function and initiator of disease. Loss of elastic fiber integrity is one of the primary contributors to ...