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RISCoupled Macroscopic and Microscopic Scale Modeling of Fibrillar Tissues and Tissue Equivalents
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Collagen mechanics are crucial to the function and dysfunction of many tissues, including blood vessels and articular cartilage, and bioartificial tissues. Previous attempts to develop computer ...
Generalized Anisotropic Inverse Mechanics for Soft Tissues
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Elastography, which is the imaging of soft tissues on the basis of elastic modulus (or, more generally, stiffness) has become increasingly popular in the last decades and holds promise for ...
Reverse Pupillary Block Slows Iris Contour Recovery From Corneoscleral Indentation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Corneoscleral indentation changes the iris contour and alters the angle between the iris and cornea. Although this effect has long been observed, the mechanism by which it occurs remains poorly ...
Multiscale, Structure-Based Modeling for the Elastic Mechanical Behavior of Arterial Walls
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Passive elastic behavior of arterial wall remains difficult to model. Although phenomenological and structural models exist, the question of how the three-dimensional network structure of the ...
Erratum: “Affine Versus Non-Affine Fibril Kinematics in Collagen Networks: Theoretical Studies of Network Behavior” [Journal of Biomechanical Engineering, 2006, 128(2), pp. 259–270]
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: In our paper, Eq. 6(b) is applicable only at small strain, not the entire strain range covered in the study. In the more general case, the average deformation gradient is determined by the ...
Affine Versus Non-Affine Fibril Kinematics in Collagen Networks: Theoretical Studies of Network Behavior
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The microstructure of tissues and tissue equivalents (TEs) plays a critical role in determining the mechanical properties thereof. One of the key challenges in constitutive modeling of TEs is ...
Deterministic Material-Based Averaging Theory Model of Collagen Gel Micromechanics
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Mechanics of collagen gels, like that of many tissues, is governed by events occurring on a length scale much smaller than the functional scale of the material. To deal with the challenge ...
Microstructural Mechanics of Collagen Gels in Confined Compression: Poroelasticity, Viscoelasticity, and Collapse
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Background: Collagen gels are important as platforms for in vitro study of cell behavior and as prototypical bioartificial tissues, but their mechanical behavior, particularly on the microscopic ...
The Modulus of Fibroblast-Populated Collagen Gels is not Determined by Final Collagen and Cell Concentration: Experiments and an Inclusion-Based Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The fibroblast-populated collagen lattice is an attractive model tissue for in vitro studies of cell behavior and as the basis for bioartificial tissues. In spite of its simplicity—containing ...
A Model of Strain-Dependent Glomerular Basement Membrane Maintenance and Its Potential Ramifications in Health and Disease
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: A model is developed and analyzed for type IV collagen turnover in the kidney glomerular basement membrane (GBM), which is the primary structural element in the glomerular capillary wall. The ...