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Nonmuscle Myosin IIA Regulates Platelet Contractile Forces Through Rho Kinase and Myosin Light-Chain Kinase
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Platelet contractile forces play a major role in clot retraction and help to hold hemostatic clots against the vessel wall. Platelet forces are produced by its cytoskeleton, which is composed of actin and nonmuscle myosin ...
Review on Cell Mechanics: Experimental and Modeling Approaches
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The interplay between the mechanical properties of cells and the forces that they produce internally or that are externally applied to them play an important role in maintaining the normal function of cells. These forces ...
Measuring the Contractile Forces of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes With Arrays of Microposts
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Human stem cellderived cardiomyocytes hold promise for heart repair, disease modeling, drug screening, and for studies of developmental biology. All of these applications can be improved by assessing the contractility of ...
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