Abstract: Systemic administration of drugs in tumors is a challenging task due to unorganized microvasculature and nonuniform extravasation. There is an imperative need to understand the transport behavior of drugs when administered ...

Abstract: In the present article, the advection–diffusion equation (ADE) having a nonlinear type source/sink term with initial and boundary conditions is solved using finite difference method (FDM). The solution of solute concentration ...

Abstract: Drug distribution in tumors is strongly dependent on tumor biological properties such as tumor volume, vasculature, and porosity. An understanding of the drug distribution pattern in tumors can help in enhancing the ...