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RISAutomating Model Generation for Image-Based Cardiac Flow Simulation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Computational fluid dynamics (CFD) modeling of left ventricle (LV) flow combined with patient medical imaging data has shown great potential in obtaining patient-specific hemodynamics information for functional assessment ...
Characterizations and Correlations of Wall Shear Stress in Aneurysmal Flow
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Wall shear stress (WSS) is one of the most studied hemodynamic parameters, used in correlating blood flow to various diseases. The pulsatile nature of blood flow, along with the complex geometries of diseased arteries, ...
Unsupervised Denoising and Super-Resolution of Vascular Flow Data by Physics-Informed Machine Learning
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: We present an unsupervised deep learning method to perform flow denoising and super-resolution without high-resolution labels. We demonstrate the ability of a single model to reconstruct three-dimensional stenosis and ...
A Coupled Lumped Parameter and Distributed Network Model for Cerebral Pulse Wave Hemodynamics
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The cerebral circulation is unique in its ability to maintain blood flow to the brain under widely varying physiologic conditions. Incorporating this autoregulatory response is necessary for cerebral blood flow (CBF) ...
Mechanical Platelet Activation Potential in Abdominal Aortic Aneurysms
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Intraluminal thrombus (ILT) in abdominal aortic aneurysms (AAA) has potential implications to aneurysm growth and rupture risk; yet, the mechanisms underlying its development remain poorly understood. Some researchers have ...
Construction of Analysis-Suitable Vascular Models Using Axis-Aligned Polycubes
Publisher: American Society of Mechanical Engineers (ASME)
Abstract: Image-based modeling is an active and growing area of biomedical research that utilizes medical imaging to create patient-specific simulations of physiological function. Under this paradigm, anatomical structures are ...
Optimization of a Y Graft Design for Improved Hepatic Flow Distribution in the Fontan Circulation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Single ventricle heart defects are among the most serious congenital heart diseases, and are uniformly fatal if left untreated. Typically, a threestaged surgical course, consisting of the Norwood, Glenn, and Fontan surgeries ...
Computational Assessment of the Relation Between Embolism Source and Embolus Distribution to the Circle of Willis for Improved Understanding of Stroke Etiology
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Stroke caused by an embolism accounts for about a third of all stroke cases. Understanding the source and cause of the embolism is critical for diagnosis and longterm treatment of such stroke cases. The complex nature of ...
A Re-Engineered Software Interface and Workflow for the Open-Source SimVascular Cardiovascular Modeling Package
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Patient-specific simulation plays an important role in cardiovascular disease research, diagnosis, surgical planning and medical device design, as well as education in cardiovascular biomechanics. simvascular is an open-source ...
Reduced Order Models for Transstenotic Pressure Drop in the Coronary Arteries
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The efficacy of reduced order modeling for transstenotic pressure drop in the coronary arteries is presented. Coronary artery disease is a leading cause of death worldwide and the computation of pressure drop in the coronary ...