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    Mechanics of Healthy and Functionally Diseased Mitral Valves: A Critical Review 

    Source: Journal of Biomechanical Engineering:;2013:;volume( 135 ):;issue: 002:;page 21007
    Author(s): Rabbah, Jean; Saikrishnan, Neelakantan; Siefert, Andrew W.; Santhanakrishnan, Arvind; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The mitral valve is a complex apparatus with multiple constituents that work cohesively to ensure unidirectional flow between the left atrium and ventricle. Disruption to any or all of the components—the annulus, leaflets, ...
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    Design of a Pulsatile Flow Facility to Evaluate Thrombogenic Potential of Implantable Cardiac Devices 

    Source: Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 004:;page 45001
    Author(s): Arjunon, Sivakkumar; Ardana, Pablo Hidalgo; Saikrishnan, Neelakantan; Madhani, Shalv; Foster, Brent; Glezer, Ari; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Due to expensive nature of clinical trials, implantable cardiac devices should first be extensively characterized in vitro. Prosthetic heart valves (PHVs), an important class of these devices, have been shown to be associated ...
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    Effect of Hinge Gap Width of a St. Jude Medical Bileaflet Mechanical Heart Valve on Blood Damage Potential—An In Vitro Micro Particle Image Velocimetry Study 

    Source: Journal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 009:;page 91008
    Author(s): Jun, Brian H.; Saikrishnan, Neelakantan; Arjunon, Sivakkumar; Min Yun, B.; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The hinge regions of the bileaflet mechanical heart valve (BMHV) can cause blood element damage due to nonphysiological shear stress levels and regions of flow stasis. Recently, a micro particle image velocimetry (خ¼PIV) ...
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    In Vitro Comparison of Doppler and Catheter Measured Pressure Gradients in 3D Models of Mitral Valve Calcification 

    Source: Journal of Biomechanical Engineering:;2013:;volume( 135 ):;issue: 009:;page 94502
    Author(s): Herrmann, Tarrah A.; Siefert, Andrew W.; Pressman, Gregg S.; Gollin, Hannah R.; Touchton, Jr. ,Steven A.; Saikrishnan, Neelakantan; Yoganathan, Ajit P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Mitral annular calcification (MAC) involves calcium deposition in the fibrous annulus supporting the mitral valve (MV). When calcification extends onto the leaflets, valve opening can be restricted. The influence of MAC ...
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