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Constitutive-Law Modeling of Microfilaments From Their Discrete-Structure Simulations—A Method Based on an Inverse Approach Applied to a Static Rod Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Twisting and bending deformations are crucial to the biological functions of several microfilaments such as DNA molecules. Although continuum-rod models have emerged as efficient tools to describe ...
Resolving the Sequence-Dependent Stiffness of DNA Using Cyclization Experiments and a Computational Rod Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Structural deformations of DNA play a central role in many biological processes, including gene expression. The structural deformations are sensitive to the material properties of the molecule, ...