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Untangling the Effect of Head Acceleration on Brain Responses to Blast Waves
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Multiple injurycausing mechanisms, such as wave propagation, skull flexure, cavitation, and head acceleration, have been proposed to explain blastinduced traumatic brain injury (bTBI). An accurate, quantitative description ...
An Integrated Musculoskeletal Finite Element Model to Evaluate Effects of Load Carriage on the Tibia During Walking
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Prior studies have assessed the effects of load carriage on the tibia. Here, we expand on these studies and investigate the effects of load carriage on joint reaction forces (JRFs) and the resulting spatiotemporal stress/strain ...
Material Properties of Rat Middle Cerebral Arteries at High Strain Rates
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Traumatic brain injury (TBI), resulting from either impact- or nonimpact blast-related mechanisms, is a devastating cause of death and disability. The cerebral blood vessels, which provide critical support for brain tissue ...
Animal Orientation Affects Brain Biomechanical Responses to Blast-Wave Exposure
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: In this study, we investigated how animal orientation within a shock tube influences the biomechanical responses of the brain and cerebral vasculature of a rat when exposed to a blast wave. Using three-dimensional finite ...
A Strain Rate-Dependent Constitutive Model for Göttingen Minipig Cerebral Arteries
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Computational simulations of traumatic brain injury (TBI) are commonly used to advance understanding of the injury–pathology relationship, tissue damage thresholds, and design of protective equipment such as helmets. Both ...
Dynamics of the Tracheal Airway and Its Influences on Respiratory Airflows: An Exemplar Study
Publisher: American Society of Mechanical Engineers (ASME)
Abstract: Respiration is a dynamic process accompanied by morphological changes in the airways. Although deformation of large airways is expected to exacerbate pulmonary disease symptoms by obstructing airflow during increased minute ...
Assessing Airflow Sensitivity to Healthy and Diseased Lung Conditions in a Computational Fluid Dynamics Model Validated In Vitro
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Computational models are useful for understanding respiratory physiology. Crucial to such models are the boundary conditions specifying the flow conditions at truncated airway branches (terminal flow rates). However, most ...
Rate- and Region-Dependent Mechanical Properties of Göttingen Minipig Brain Tissue in Simple Shear and Unconfined Compression
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Traumatic brain injury (TBI), particularly from explosive blasts, is a major cause of casualties in modern military conflicts. Computational models are an important tool in understanding the underlying biomechanics of TBI ...