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    Remodeling of Murine Branch Pulmonary Arteries Under Chronic Hypoxia and Short-Term Normoxic Recovery 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 008:;page 84501-1
    Author(s): Ramachandra, Abhay B.; Jiang, Bo; Jennings, Isabella R.; Manning, Edward P.; Humphrey, Jay D.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Chronic hypoxia plays a central role in diverse pulmonary pathologies, but its effects on longitudinal changes in the biomechanical behavior of proximal pulmonary arteries remain poorly understood. Similarly, effects of ...
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    Computational Simulation of the Adaptive Capacity of Vein Grafts in Response to Increased Pressure 

    Source: Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 003:;page 31009
    Author(s): Ramachandra, Abhay B.; Sankaran, Sethuraman; Humphrey, Jay D.; Marsden, Alison L.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Vein maladaptation, leading to poor longterm patency, is a serious clinical problem in patients receiving coronary artery bypass grafts (CABGs) or undergoing related clinical procedures that subject veins to elevated blood ...
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    Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice 

    Source: Journal of Biomechanical Engineering:;2022:;volume( 144 ):;issue: 008:;page 81008-1
    Author(s): Ramachandra, Abhay B.; Mikush, Nicole; Sauler, Maor; Humphrey, Jay D.; Manning, Edward P.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Competent elastic fibers are critical to the function of the lung and right circulation. Murine models of elastopathies can aid in understanding the functional roles of the elastin and elastin-associated glycoproteins that ...
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