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    Enzymatic Digestion of the Intervertebral Disc Alters Intradiscal Injection and Leakage Mechanics 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 011:;page 111008-1
    Author(s): Appel, Zachary; Michalek, Arthur J.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Intradiscal injection is required to deliver therapeutic agents to the intervertebral disc (IVD) nucleus pulposus (NP). However, injectate leakage following needle retraction may result in decreased treatment efficacy and ...
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    Mapping of Intervertebral Disk Annulus Fibrosus Compressive Properties Is Sensitive to Specimen Boundary Conditions 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 004:;page 44501
    Author(s): Duclos, Sarah E.; Michalek, Arthur J.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Predicting the mechanical behavior of the intervertebral disk (IVD) in health and in disease requires accurate spatial mapping of its compressive mechanical properties. Previous studies confirmed that residual strains in ...
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    A Proximally-Adjustable Variable Length Intramedullary Nail: Ex Vivo Quasi-Static and Cyclic Loading Evaluation 

    Source: Journal of Medical Devices:;2017:;volume( 011 ):;issue: 004:;page 45001
    Author(s): Hedgeland, Mark J.; Martin Clark, Jr., Alexander; Ciani, Mario J.; Michalek, Arthur J.; Kuxhaus, Laurel
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: An adjustable-length intramedullary (IM) nail may reduce both complications secondary to fracture fixation and manufacturing costs. We hypothesized that our novel nail would have suitable mechanical performance. To test ...
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    Bridging the Gap: Science and Technology Policy in the (Bio)Engineering Classroom 

    Source: Journal of Biomechanical Engineering:;2020:;volume( 142 ):;issue: 011:;page 0114703-1
    Author(s): Kuxhaus, Laurel; Michalek, Arthur J.; Martin, Stephen M.; Steinbacher, Jeremy L.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Engineers and scientists have a key role to play in the creation and implementation of government policy. Policymakers need access to the technical expertise that is critical to our national progress and security; however, ...
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