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Anthropomorphic Model of Intrathecal Cerebrospinal Fluid Dynamics Within the Spinal Subarachnoid Space: Spinal Cord Nerve Roots Increase Steady-Streaming
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Cerebrospinal fluid (CSF) dynamics are thought to play a vital role in central nervous system (CNS) physiology. The objective of this study was to investigate the impact of spinal cord (SC) nerve roots (NR) on CSF dynamics. ...
Nonuniform Moving Boundary Method for Computational Fluid Dynamics Simulation of Intrathecal Cerebrospinal Flow Distribution in a Cynomolgus Monkey
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: A detailed quantification and understanding of cerebrospinal fluid (CSF) dynamics may improve detection and treatment of central nervous system (CNS) diseases and help optimize CSF system-based delivery of CNS therapeutics. ...
Characterization of the Discrepancies Between Four Dimensional Phase Contrast Magnetic Resonance Imaging and In Silico Simulations of Cerebrospinal Fluid Dynamics
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The purpose of the present study was to compare subjectspecific magnetic resonance imaging (MRI)based computational fluid dynamics (CFD) simulations with timeresolved threedirectional (3D) velocityencoded phasecontrast MRI ...
Cerebrospinal Fluid Flow Impedance is Elevated in Type I Chiari Malformation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Diagnosis of Type I Chiari malformation (CMI) is difficult because the most commonly used diagnostic criterion, cerebellar tonsillar herniation (CTH) greater than 3–5 mm past the foramen magnum, has been found to have ...