Abstract: Patientspecific cardiovascular simulations can provide clinicians with predictive tools, fill current gaps in clinical imaging capabilities, and contribute to the fundamental understanding of disease progression. However, ...

Abstract: For newborns diagnosed with pulmonary atresia or severe pulmonary stenosis leading to insufficient pulmonary blood flow, cyanosis can be mitigated with placement of a modified Blalock–Taussig shunt (MBTS) between the ...

Abstract: We propose svMorph, a framework for interactive virtual sculpting of patient-specific vascular anatomic models. Our framework includes three tools for the creation of tortuosity, aneurysms, and stenoses in tubular vascular ...

Abstract: Blood pressure gradient (ΔP) across an aortic coarctation (CoA) is an important measurement to diagnose CoA severity and guide treatment. While invasive cardiac catheterization is the clinical gold-standard for measuring ...

Abstract: Single ventricle heart defects are among the most serious congenital heart diseases, and are uniformly fatal if left untreated. Typically, a threestaged surgical course, consisting of the Norwood, Glenn, and Fontan surgeries ...

Abstract: Vein maladaptation, leading to poor longterm patency, is a serious clinical problem in patients receiving coronary artery bypass grafts (CABGs) or undergoing related clinical procedures that subject veins to elevated blood ...

Abstract: Background: Reduced exercise capacity is nearly universal among Fontan patients, though its etiology is not yet fully understood. While previous computational studies have attempted to model Fontan exercise, they did not ...

Abstract: The formula for E(t) in Appendix A (p. 11) should be corrected asE(t)={Emax En(0.3tsvst)+Eoffset,ttsvs≤3.33Eoffset,elsewhere

Abstract: Patient-specific simulation plays an important role in cardiovascular disease research, diagnosis, surgical planning and medical device design, as well as education in cardiovascular biomechanics. simvascular is an open-source ...

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