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RISAn Axisymmetric Boundary Integral Model for Incompressible Linear Viscoelasticity: Application to the Micropipette Aspiration Contact Problem
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The micropipette aspiration test has been used extensively in recent years as a means of quantifying cellular mechanics and molecular interactions at the microscopic scale. However, previous ...
An Axisymmetric Boundary Integral Model for Assessing Elastic Cell Properties in the Micropipette Aspiration Contact Problem
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The micropipette aspiration technique has been used extensively in recent years to measure the mechanical properties of living cells. In the present study, a boundary integral formulation with ...
An Axisymmetric Boundary Element Model for Determination of Articular Cartilage Pericellular Matrix Properties In Situ via Inverse Analysis of Chondron Deformation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The pericellular matrix (PCM) is the narrow tissue region surrounding all chondrocytes in articular cartilage and, together, the chondrocyte(s) and surrounding PCM have been termed the chondron. ...
The Dynamic Mechanical Environment of the Chondrocyte: A Biphasic Finite Element Model of Cell-Matrix Interactions Under Cyclic Compressive Loading
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Cyclic mechanical loading of articular cartilage results in a complex biomechanical environment at the scale of the chondrocytes that strongly affects cellular metabolic activity. Under dynamic ...
Alterations in the Mechanical Properties of the Human Chondrocyte Pericellular Matrix With Osteoarthritis
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: In articular cartilage, chondrocytes are surrounded by a pericellular matrix (PCM), which together with the chondrocyte have been termed the “chondron.” While the precise function of the PCM is ...