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    Freezing-Assisted Intracellular Drug Delivery to Multidrug Resistant Cancer Cells 

    Source: Journal of Biomechanical Engineering:;2009:;volume( 131 ):;issue: 007:;page 74513
    Author(s): Ka Yaw Teo; Bumsoo Han
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The efficacy of chemotherapy is significantly impaired by the multidrug resistance (MDR) of cancer cells. The mechanism of MDR is associated with the overexpression of certain adenosine ...
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    Spatiotemporal Measurement of Freezing-Induced Deformation of Engineered Tissues 

    Source: Journal of Biomechanical Engineering:;2010:;volume( 132 ):;issue: 003:;page 31003
    Author(s): Ka Yaw Teo; J. Craig Dutton; Bumsoo Han
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In order to cryopreserve functional engineered tissues (ETs), the microstructure of the extracellular matrix (ECM) should be maintained, as well as the cellular viability since the functionality ...
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