Abstract: The synthesis of functional molecular linkages is constrained by difficulties in fabricating nanolinks of arbitrary shapes and sizes. Thus, classical mechanism synthesis methods, which assume the ability to manufacture any ...

Abstract: A number of machine learning methods have been recently proposed to circumvent the high computational cost of the gradient-based topology optimization solvers. By and large, these methods show tight generalizability to ...

Abstract: Orthotic treatments for knee osteoarthritis (OA) typically rely on simple mechanisms such as three-point bending straps and single-pin hinges. These commonly prescribed braces cannot treat bicompartmental knee OA, do not ...

Abstract: Designing the 3D layout of interconnected systems (SPI2), which is a ubiquitous task in engineered systems, is of crucial importance. Intuitively, it can be thought of as the simultaneous placement of (typically rigid) ...

Abstract: Three-dimensional spatial packaging of interconnected systems with physical interactions (SPI2) design plays a vital role in the functionality, operation, energy usage, and life cycle of practically all engineered systems, ...

Abstract: Natural nanomechanisms such as capillaries, neurotransmitters, and ion channels play a vital role in the living systems. But the design principles developed by nature through evolution are not well understood and, hence, ...