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RISThe “Stressful” Life of Cell Adhesion Molecules: On the Mechanosensitivity of Integrin Adhesome
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Cells have evolved into complex sensory machines that communicate with their microenvironment via mechanochemical signaling. Extracellular mechanical cues trigger complex biochemical pathways in the cell, which regulate ...
The Role Of Extracellular Matrix Elasticity and Composition In Regulating the Nucleus Pulposus Cell Phenotype in the Intervertebral Disc: A Narrative Review
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Intervertebral disc (IVD) disorders are a major contributor to disability and societal health care costs. Nucleus pulposus (NP) cells of the IVD exhibit changes in both phenotype and morphology with agingrelated IVD ...