Abstract: Recent advances in modulating collagen building blocks enable the design and control of the microstructure and functional properties of collagen matrices for tissue engineering and regenerative medicine. However, this is ...

Abstract: Preservation of structural integrity inside cells and at cellextracellular matrix (ECM) interfaces is a key challenge during freezing of biomaterials. Since the postthaw functionality of cells depends on the extent of ...

Abstract: During cryopreservation, ice forms in the extracellular space resulting in freezinginduced deformation of the tissue, which can be detrimental to the extracellular matrix (ECM) microstructure. Meanwhile, cells dehydrate ...

Abstract: The human body represents a collection of interacting systems that range in scale from nanometers to meters. Investigations from a systems perspective focus on how the parts work together to enact changes across spatial ...